background: reactive oxygen species (ros) have important role in the etiology and pathogenesis of rheumatoid arthritis (ra). we investigated the effect of conjugated linoleic acids (clas) and vitamin e on lipid peroxidation. methods: in a randomized, double-blind placebo, controlled, clinical trial 87 patients with active ra were enrolled. they were divided into 4 groups, received one of the fo...

rheumatoid arthritis is the most common inflammatory joint disease with 1 percent prevalence in community which presents with symmetrical polyarthritis of hands with inflammatory behavior. several studies in recent years were conducted for evaluation of inflammatory cytokines such as il1-α (interlukin 1α) and tnf- α (tumor necrosis factor) in rheumatologic disorders including rheumatoid arthrit...

background rheumatoid arthritis (ra) is a chronic inflammatory disease with extra- articular involvement. eyes in particular are one of the most common sites of involvement in rheumatoid arthritis. on the other hand, dry eye syndrome is the most common conflict in terms of management. particular studies suggested dry eye has been associated with greater rheumatoid arthritis severity, but its as...

background: single-nucleotide polymorphism (snp) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (ptpn22) has been shown to be a risk factor for different autoimmune diseases. this study explored the association of 1858 c/t snp with rheumatoid arthritis (ra) and celiac disease (cd) in a region covering south-west of iran. methods: totally, 52 patients with cd, 120 patien...

background: this study aimed to compare the percentage of detection of periarthritis in patients with rheumatoid arthritis using clinical examination and ultrasound methods. materials and methods: this study is a cross?sectional study which was conducted in al?zahra hospital (isfahan, iran) during 2014–2015. in our study, ninety patients were selected based on the american college of rheumatolo...

Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...

objective: anti-cyclic citrullinated peptide (anti-ccp) antibodies are highly specific markers for rheumatoid arthritis (ra) and useful for predicting rheumatoid arthritis (ra) development and progression. we assessed the diagnostic value of anti-ccp antibodies in our patients with ra. materials and methods: anti-ccp antibodies and rheumatoid factor (rf) titers were determined in 247 serum sam...