نتایج جستجو برای: adrenoreceptors

تعداد نتایج: 330  

2015
Utkarsh Kohli André Diedrich Prince J. Kannankeril Mordechai Muszkat Gbenga G. Sofowora Maureen K. Hahn Randy D. Blakely Daniel Kurnik

3 Utkarsh Kohli, M.D., André Diedrich, M.D., Ph.D., Prince J. Kannankeril, M.D., 4 Mordechai Muszkat, M.D., Gbenga G. Sofowora, M.D., Maureen K. Hahn, 5 Ph.D., Brett A. English, Pharm.D., Ph.D., Randy D. Blakely, Ph.D., C. Michael 6 Stein, M.D., Daniel Kurnik, M.D. 7 8 Departments of Medicine, Pharmacology, Psychiatry, Biomedical Engineering and 9 Pediatrics, Divisions of Clinical Pharmacology ...

2015
Alexander Samoshkin Marino Convertino Chi T. Viet Jeffrey S. Wieskopf Oleg Kambur Jaclyn Marcovitz Pinkal Patel Laura S. Stone Eija Kalso Jeffrey S. Mogil Brian L. Schmidt William Maixner Nikolay V. Dokholyan Luda Diatchenko

The primary molecular target for clinically used opioids is the μ-opioid receptor (MOR). Besides the major seven-transmembrane (7TM) receptors, the MOR gene codes for alternatively spliced six-transmembrane (6TM) isoforms, the biological and clinical significance of which remains unclear. Here, we show that the otherwise exclusively intracellular localized 6TM-MOR translocates to the plasma mem...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Natalia V Neverova Shane A Saywell Lisa J Nashold Gordon S Mitchell Jack L Feldman

In vitro long-term facilitation (ivLTF) is a novel form of activity-independent postsynaptic enhancement of AMPA receptor function in hypoglossal (XII) motoneurons that can be induced by intermittent activation of 5-HT2 receptors. In vivo respiratory long-term facilitation (LTF) is characterized by a persistent 5-HT2 receptor-dependent increase in respiratory motor output or ventilation after e...

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