the antidepressant effects of aloe vera hydro alcoholic extract at different concentrations were compared with the fluoxetine-treated and the control groups of mice using forced - swimming, fst and open box, oft tests. the mice were evaluated in five groups (control, taking aloe vera at the dosage levels of 150 mg/kg, 300 mg/kg, and 450 mg/kg, and finally fluoxetine at a dose of 10 mg/kg) by th...

Background and Objectives: Exercise and nutrition are two effective factors in controlling diabetes-induced metabolic disorders. The aim of this study was to assess effects of aloe vera and swimming training on lipid profile of the diabetic rats. Materials and Methods: In this experimental study, 72 diabetic rats were selected and divided into nine groups of eight rats, including 1) four weeks...

For centuries, Aloe Vera has been used by many different cultures. The ancient Greeks, the Romans, the Babylonians, Indians and the Chinese have all used Aloe Vera as a medicinal plant. One of the common experimental cancer models is sarcoma-180. When Aloe was administered to mice bearing S-180 tumors, the tumor growth was inhibited. Aloe vera is a dietary supplement and not a regulated drug. T...

Background: Diabetes is a metabolic disease that is associated with hyperglycemia and infertility. Previous studies indicate that aloe vera may positively affect the blood glucose and fertility. Objective: the present study was carried out to evaluate effect of aloe vera on serum oxidant/antioxidant activity and reproductive hormones following experimental diabetes. Methods: sixty adults male ...

The gastrointestinal tract of neonates is sensitive to dietary manipulations. When nursing mothers use Aloe vera, their babies are at risk of indirect exposure to Aloe vera via breast feeding or directly as health supplements. The effects of orally administered extracts of Aloe vera in unweaned rats were investigated. Six day old Sprague-Dawley rats were gavaged with aqueous or alcohol extracts...

OBJECTIVES Oral submucous fibrosis (OSMF) is a potentially malignant disorder predominantly seen in the Indian subcontinent due to areca nut, tobacco and their products. The aim of the present study was to compare the efficacy of oxitard and aloe vera in the management of OSMF. MATERIAL AND METHODS 120 subjects with OSMF were included in the study. The patients were clinico-pathologically dia...

The aim of the investigation was to prepare nimesulide emulsion for incorporation in Aloe vera gel base to formulate 'nimesulide - Aloe vera transemulgel' (NAE) and to carryout in-vitro assessment and in-vivo anti-inflammatory studies of the product. Although the use of nimesulide is banned for oral administration, due to its potential for inducing hepatotoxicity and thrombocytopenia, the use o...

Purpose: The objective of this work was to prepare and evaluate fast dissolving tablets of the nutraceutical, freeze dried Aloe vera gel. Methods: Fast dissolving tablets of the nutraceutical, freeze-dried Aloe vera gel, were prepared by dry granulation method. The tablets were evaluated for crushing strength, disintegration time, wetting time, friability, drug content and drug release. A 3 2 f...