As the use of molecularly targeted agents, which are anticipated to increase overall survival (OS)and progression-free survival (PFS) but not necessarily tumor response, has increased in oncology, there has been a corresponding increase in the recommendation and use of randomized phase II designs. Such designs reduce the potential for bias, existent in comparisons with historical controls, but ...

The paper deals with the deployment of XML-related technologies in Cultural Heritage applications concerning the encoding of temporal semantics in the digital version of historical documents. Since written sources have often the same importance as material evidence in medieval archaeology, our approach can be applied to the development of tools for the support of archaeological research. In pre...

4BSTRACT The paper deals with the deployment of XML-related technologies in Cultural Heritage applications concerning the :ncoding of temporal semantics in the digital version of historical documents. Since written sources have often the same importance as material evidence in mcdicval archaeology, our approach can be applied to the development of tools for the support of archaeological researc...

when neo-conservative came to power, they acquired twofold behavioral models towards nuclear case of iran. mainly, this derives of essential conflicts of the two state, and partly, because of differential regional and international interests and favorites of u.s. and islamic republic of iran. with studying iranian nuclear viewpoints, we analyze the mentioned american strategy and tactics, with ...

The difficulty in the description, the analysis and the comprehension of cultural heritage often stands on the fact that buildings undergo numerous changes over time. Three factors condition the knowledge of historical heritage. Firstly, 3D reconstructions of heritage buildings focus normally on existing states and not on the management of historical evolutions. Secondly, if on one side iconogr...