contact: A contest between three Japanese tertiary care centers Hitoshi Honda, MD; Tomoko Sakihama, RN, CNIC, MSN; Sanjay Saint, MD, MPH; Karen Fowler, MPH; Toru Kamiya, MD; Yumiko Sato, RN, CNIC, MSN; Ritsuko Iuchi, RN, CNIC, MSN; Yasuharu Tokuda, MD MPH; Division of Infectious Diseases and Department of Medicine, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan; Department of Nursi...

1 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI. 2 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. 3 Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. 4 Department of Pathology, University of Vermont, Burlington, VT. 5 Department of Environmental Health Sciences,...

fluids for various industrial applications because of their excellent thermal performance. this study analytically and experimentally examines the effects of nanoparticle dispersion on the entropy generation of eg–al2o3 nanofluid flows through a helical pipe as a heat exchanger under constant wall heat flux thermal boundary condition in laminar regime. it is found that adding nanoparticles impr...

Pressure-sensitive (P) neurons located in the leech CNS form elaborate terminal arbors in the body wall of the animal during mid-embryogenesis. In the experiments discussed here, arbor development in the target region was studied in intact, unanesthetized leech embryos using time-lapse video microscopy of individual, fluorescently stained P neurons. Analysis of time-lapse recordings made over a...

In a complex nervous system, neuronal functional diversity is reflected in the wide variety of dendritic arbor shapes. Different neuronal classes are defined by class-specific transcription factor combinatorial codes. We show that the combination of the transcription factors Knot and Cut is particular to Drosophila class IV dendritic arborization (da) neurons. Knot and Cut control different asp...

Dendritic arbors are compartments of neurons dedicated to receiving synaptic inputs. Their shape is an outcome of both the intrinsic genetic program and environmental signals. The microtubules and actin cytoskeleton are both crucial for proper dendritic morphology, but how they interact is unclear. The present study demonstrates that microtubule plus-end tracking protein CLIP-170 and actin-bind...

Sijia Liu1,2,∗, Haiming Chen1,∗, Scott Ronquist1,∗, Laura Seaman1, Nicholas Ceglia3, Walter Meixner1, Lindsey A. Muir4, Pin-Yu Chen5, Gerald Higgins1, Pierre Baldi3,6, Steve Smale7,8, Alfred Hero2, Indika Rajapakse1,9,∗∗ Dept. of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA Dept. of Electrical Engineering & Computer Science, University of Michigan, A...

In vivo imaging of optic tectal neurons in the intact Xenopus tadpole permits direct observation of the structural dynamics that occur during dendritic arbor formation. Based on images of single DiI-labeled neurons collected at daily intervals over a period of 6 d, we divided tectal cell development into three phases according to the total length of the dendritic arbor. During phase 1, the cell...

Molecular dynamic simulation is a powerful method that monitors all variations in the atomic level in explicit solvent. By this method we can calculate many chemical and biochemical properties of large scale biological systems. In this work all-atom molecular dynamics simulation of polyalanine (PA) was investigated in the presence of 0.224, 0.448, 0.673, 0.897 and 1.122 M of guanidinium chlorid...

Patrick Feglo, Yaw Adu-Sarkodie, Lord Ayisi, Ruchika Jain, Rachel R. Spurbeck, A. Cody Springman, N. Cary Engleberg, Duane W. Newton, Chuanwu Xi, Seth T. Walk* Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Hospital and Health Systems, Ann Arbor, Mich...