Background and Objective: This study was carried out to isolate lytic bacteriophages against Pseudomonas aeruginosa and analyze their biological characteristics and antibacterial effects on other clinical isolates of bacteria. Methods: Isolating two lytic bacteriophages against two strains of P. aeruginosa was carried out using the double-layer agar method. After investigating the antibacteria...

Objective(s): Bacteriophages are infectious replicating entities that are under consideration as antimicrobial bioagents to control bacterial infections. As an alternative or supplement to antibiotics, bacteriophages can be used to circumvent the resistance to existing antibiotics. The aim of this study was to assess the synergistic effect of a naturally isolated phage...

Abstract Background Bacterial canker and subsequent gummosis are caused by multiple pathogens lead to significant yield productivity losses in sweet cherry cultivation Turkey. This study identified that Pseudomonas syringae pathovars were responsible for bacterial on orchards using classical molecular methods evaluated the biocontrol effects of bacteriophages against P. pv. syringae. Results Pa...

The efficacy of cell-free gene expression (CFE) has been considerably improved in the last decade. As a consequence, CFE systems have now capacity to express DNAs composed tens genes encoding for complex self-assembly processes. A recent example is demonstration that infectious bacteriophages can be synthesized one-pot reactions from their genomes. This landmark result opens new perspectives pr...

Salmonella enterica serovar Enteritidis is one of the most common causes of Salmonellosis worldwide. Utilization of bacteriophages as prophylactic agents is a practical solution to prevent Salmonellosis in ready-to-eat products. Shelf stability is one of the desirable properties for prophylactic bacteriophages. Here, we describe the phenotype, genome, and phylogeny of fSE1C and fSE4S Salmonella...

The lack of practical methods for bacterial separation remains a hindrance for the low-cost and successful development of rapid detection methods from complex samples. Antibody-tagged magnetic particles are commonly used to pull analytes from a liquid sample. While this method is well-established, improvements in capture efficiencies would result in an increase of the overall detection assay pe...

Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to pose a threat to public health and that bacteriophages are frequently used as m...

Escherichia coli serogroup O26 consists of enterohemorrhagic E. coli (EHEC) and atypical enteropathogenic E. coli (aEPEC). The former produces Shiga toxins (Stx), major determinants of EHEC pathogenicity, encoded by bacteriophages; the latter is Stx negative. We have isolated EHEC O26 from patient stools early in illness and aEPEC O26 from stools later in illness, and vice versa. Intrapatient E...

With its capacity for anaerobic methane oxidation and denitrification, the bacterium Methylomirabilis oxyfera plays an important role in natural ecosystems. Its unique physiology can be exploited for more sustainable wastewater treatment technologies. However, operational stability of full-scale bioreactors can experience setbacks due to, for example, bacteriophage blooms. By shaping microbial ...

BACKGROUND In recent years, antibiotic resistance has been indicated as a paramount threat to public health. The use of bacteriophages appears to be a safer alternative for the control of bacterial infections. OBJECTIVES The present study aims to explore sewage water for the presence of indigenous bacteriophages, and to investigate their antibacterial potential against Methicillin-resistant S...