Introduction A compartmental syndrome is defined as a condition in which elevated pressure in an osteofascial compartment produces dysfunction or necrosis of the enclosed tissues (Matsen, 1975). The anterior tibial compartment (ATC) is surrounded by dense fibrous tissue, bone and interosseous membrane forming a rigid boundary, thus making raised pressure especially likely to be damaging. The AT...

Anaplastic thyroid cancer (ATC) is a rare malignancy and has a very poor prognosis due to its aggressive behavior and resistance to treatment. No effective treatment modalities are currently available. Lenvatinib has shown encouraging results in the patients with radioiodine-refractory differentiated thyroid cancer (DTC); however, lenvatinib monotherapy has a relatively low efficacy against ATC...

The Air Traffic Control (ATC) domain is concerned with controlling and monitoring air traffic from a source airport to a destination airport. A number of cooperating agents distributed throughout the ATC environment ensure that a safe, orderly and expenditious movement of traffic in airspace is achieved. Starting with a general discussion on the mechanics of ATC especially its operation, the pa...

OBJECTIVES To investigate the extent to which pharmacoepidemiologic groupings are homogeneous in terms of clinical properties. METHODS In our analysis, we classified drug subgroups from the pharmacoepidemiologic Anatomical Therapeutic Chemical (ATC) classification system based on clinical drug properties. We established mappings from ATC fifth level drug entities to drug property annotations ...

Improving of ATC is an important issue in the current de-regulated environment of power systems. The Available Transfer Capability (ATC) of a transmission network is the unutilized transfer capabilities of a transmission network for the transfer of power for further commercial activity, over and above already committed usage. Power transactions between a specific seller bus/area and a buyer bus...

New sesquiterpenoid derivatives from Solanum septemlobum with cytotoxicities Lei Zhang, Hai-Qing Lin, Gui-Sheng Li, Xi-Dian Yue & ShengJun Dai a School of Pharmaceutical Science, Yantai University, Yantai 264005, P.R. China b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical Coll...

Abstract Background Product innovation in the pharmaceutical market is, although not exclusively, a new product with capacity to generate value. Thus, it must represent an invention through investment research and development, commercial monopoly. The aim is identify trends by Marketing Authorization (MA) granted Portugal. Methods Quantitative descriptive study based on data (years 2017 2021) f...

Dissociation-induced apoptosis of human embryonic stem cells (hESCs) hampers their large-scale culture. Herein we leveraged the mechanosensitivity of hESCs and employed, to our knowledge, a novel technique, acoustic tweezing cytometry (ATC), for subcellular mechanical stimulation of disassociated single hESCs to improve their survival. By acoustically actuating integrin-bound microbubbles (MBs)...

Analytical target cascading (ATC) is a methodology for translating system-level design targets to subsystem and component design specifications in hierarchically decomposed optimal system design problems. In previous work we extended the ATC formulation to account for uncertainties, where the bounds of the probabilistic design constraints were chosen arbitrarily and held fixed during the ATC pr...