Several estrogens of diverse classes, namely stilbene estrogens, steroidal estrogens, phytoestrogens, mycoestrogens, lignans, and bisphenol A, were studied for their ability to interfere with the assembly of microtubules under cell-free conditions. Inhibition of microtubules in intact cells may lead to the induction of micronuclei and aneuploidy and thereby contribute to estrogen-mediated carci...

migration of compounds from packaging materials is one of the most important aspects of food safety. epoxy resins have been in inner coatings of food cans since the 1960s. these resins can be produced from bisphenol-a diglycidyl ether (badge) that is also utilized as a starter. migration of potentially toxic compounds in epoxy resins used for commercial cans is a very important food safety issu...

results the main pathological finding observed in the prostrate and seminal vesicle glands, using light microscope, revealed congestion in the connective tissue and vacuolization in the secretory units of epithelial cells and epithelium rupture at 50 and 100 µg/kg doses of bpa. ultrastructure study showed vacuolization of mitochondria, condensation of nuclei and disappearance of nucleus in the ...

background : this research provides an insight into exposure information and particle size distributions of bisphenol a (bpa), a common environmental hormone, at polycarbonate (pc) molding plants in southern taiwan. methods : the inhalable dust sampler as iom and the micro-orifice uniform deposition impactor (moudi) were used for samples collection to evaluate the level and particle size distri...

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