background: bisphenol a (bpa) is one of the hazardous materials causing disruption of endocrine pathways. due to water contamination by this component from multiple sources and the associated health problems, bpa has been the focus of multiple studies. it has been proved that bpa may cause harm because of its impact on estrogenic receptors in human and other organisms. methods: in this study, t...

Background: Bisphenol A (BPA) is one of the hazardous materials causing disruption of endocrine pathways. Due to water contamination by this component from multiple sources and the associated health problems, BPA has been the focus of multiple studies. It has been proved that BPA may cause harm because of its impact on estrogenic receptors in human and other organisms. Methods: In this study, ...

BACKGROUND Bisphenol AF has been acknowledged to be useful for the production of CF3-containing polymers with improved chemical, thermal, and mechanical properties. Because of the lack of adequate toxicity data, bisphenol AF has been nominated for comprehensive toxicological characterization. OBJECTIVES We aimed to determine the relative preference of bisphenol AF for the human nuclear estrog...

background: bisphenol-a is categorized as a toxic and refractory organic matter. ultrasonic process considered as an effective method for degradation of refractory organic matters in the environment which is achieved by the production of fine bubbles through cavitation process. this study is conducted for assessment of the toxicity of effluents containing bisphenol-a which was treated by ultras...

bisphenol a, 2,2-bis(4,4-dihyroxyphenyl propane) is the raw material for the production of important synthetic polymers such as epoxyresins, polycarbonates and polysulphones. during the last twenty years the anual production of bisphenol-a has been continuously increasing. a,b,c cqrves shows the consumption pattern of bisphenol-a (19601972) • epoxy resins are used for the production of adhessiv...

The environmental estrogen bisphenol A, orally introduced into the body, passes through the liver and modulates the endocrine system to elicit irreversible changes in the functioning of reproduction. To elucidate the actual and dynamic metabolism of bisphenol A in the liver before its arrival at target organs, this study evaluated the metabolism and disposition of the compound within the passag...

In male rats challenged with the environmental estrogen bisphenol A, the compound is highly glucuronidated in the liver and is excreted largely into the bile. Given that in pregnancy the microsomal glucuronidation toward bisphenol A is attenuated, we hypothesized that elimination of bisphenol A from the liver may be reduced in pregnancy. This study was conducted to trace the elimination of bisp...

An endocrine disrupter, bisphenol-A is widely used in the production of plastics and coatings. Recently, it was reported that bisphenol-A affected neurotransmitters in the mammalian brain. On the basis of these reports, it was considered that bisphenol-A affected neuronal differentiation. In this study, the morphological changes in nerve growth factor (NFG)-induced differentiation caused by bis...