stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. they are found in multicellular organisms. in mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. in ad...

Objective(s) It is believed that the mesenchymal stem cell (MSC) differentiation and proliferation are the results of activation of wnt signaling pathway. On the other hand, lithium chloride is reported to be able to activate this pathway. The objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived MSC. Materials and ...

this study discusses the effect of complexes of chitosan grafted polyethylenimine(ch-pei) with plasmid dna on viability of mesenchymal stem cells(mscs) derived from human marrow. ch-pei/pdna nanoparticles were synthesized through the complex coacervation method using pires plasmid containing green fluorescent protein (gfp) gene. to confirm the complexation, samples were run through an agarose g...

To evaluate pathogenicity of 3 Chicken Anemia Virus isolates-CV1, CV2 and CV3 respectively - the current experiment carried out. After tittering of the viruses, 30 one day old SPF chicks were grouped and intramuscularly inoculated with each isolate in a separate group. Two other groups as positive and control groups were inoculate with a live vaccine virus and normal saline respectively. During...

Sulphur mustard (SM) is an alkylating agent that was first used as a chemical warfare agent during the First World War in 1917. SM is readily absorbed from the skin, respiratory and gastrointestinal tract and is distributed to several organs. SM may act rapidly and persistently upon DNA replicating mechanism of the individual cells during mitosis particularly in the hematopoietic system. O...

Background: Although numerous natural or synthetic drugs have been tested for their radioprotective capacity, yet no suitable drug has been introduced for routine clinical use. In this study the radioprotective effect of "a new herbal immunomodulator" commercially known as IMOD, specifically made to decrease the side effects of HIV virus, was investigated on mouse bone marrow cells. M...

sulphur mustard (sm) is an alkylating agent that was first used as a chemical warfare agent during the first world war in 1917. sm is readily absorbed from the skin, respiratory and gastrointestinal tract and is distributed to several organs. sm may act rapidly and persistently upon dna replicating mechanism of the individual cells during mitosis particularly in the hematopoietic system. of 233...

Abstract Background In Acute Myeloid Leukemia (AML), malignant clones of immature myeloid cells (primarily blasts) proliferate, replace bone marrow, circulate in blood and invade other tissues. The unique presentation of unilateral ptosis and unilateral eyelid swelling in AML has been reported during the present study. Case Report A 7-year-old girl was encountered with progressively increa...