Previous studies show that surface immobilized bisphosphonates improve the fixation of stainless steel screws in rat tibia after 2-8 weeks of implantation. We report here about the immobilization of a potent bisphosphonate, zoledronate, to crosslinked fibrinogen by the use of another technique, i.e. ethyl-dimethyl-aminopropylcarbodiimide (EDC)/imidazole immobilization. Bone fixation of zoledron...

PURPOSE The most important part of facial bone fracture treatment is immobilization. Bandaging of the fractured mandible was the first immobilization device used in ancient Greece. Since then, various methods with different shapes and uses were introduced in the treatment of maxillofacial trauma patients. Intermaxillary fixation (IMF) with bone screws was first used in 1981. This technique has ...

The incidence of failure in spinal fusion is still too high (Barr 1951). It has been stated that if the operation could be undertaken with little or no danger from shock, subsequent thrombosis and embolism, and if it would offer a high prospect of firm union with a short period of bed rest, then a larger proportion of patients would be grafted (Young 1953). Spinal fusion was the subject of an e...

OBJECTIVE The aim of the present study was to compare calcium sulfate (CAS) and polymethylmethacrylate (PMMA) bone cements used for the augmentation of a failed pedicle screw with biomechanical pull-out strength (POS) testing. METHODS Thirty lumbar vertebrae were harvested from 6 calves and bone mineral densities (BMD) were measured. Primary polyaxial pedicle screws were randomly inserted and...

BACKGROUND Screws placed in the distal fibula may not have satisfactory purchase during internal fixation of an osteoporotic ankle fracture. Tibia-pro-fibula screws that extend from the fibula into the distal tibial metaphysis provide additional purchase. The purpose of this study was to investigate if purchase of these screws can be enhanced further by injecting calcium sulfate and calcium pho...

BACKGROUND In fracture treatment, adequate fixation of implants is crucial to long-term clinical performance. Bisphosphonates (BP), potent inhibitors of osteoclastic bone resorption, are known to increase peri-implant bone mass and accelerate primary fixation. However, adverse effects are associated with systemic use of BPs. Thus, Zoledronic acid (ZOL) a potent BP was loaded on bone screws and ...

PURPOSE To enhance the diminished screw purchase in cancellous, osteoporotic bone following the fixation of posterior pelvic ring injuries by iliosacral screws an increased bone-implant contact area using modificated screws, techniques or bone cement may become necessary. The aim of the study was to identify sites within the pathway of iliosacral screws requiring modifications of the local bone...

Bone fracture due to an accident, aging or diseases is a feature of everyday life. One of the principal methods of repair and reconstruction of such a fracture is based on drilling the bone and fixing its separate parts together using screws, wires and plates. Morphology of the drilled hole surface and fixative components such as screws, pins and hooks influences strength of the bonds between t...

Nowadays, with the advent of mini-implants, maximum anchorage has become possible and unwanted side effects have been reduced to a minimum. Mini-implants which are also known as Temporary Anchorage Devices (TADs) are small titanium bone screw or stainless steel bone screws which are placed either in buccal alveolar bone or the palatal side. These bone screws can be placed on the paramedian area...

Osteosynthesis screws and titanium or resorbable pins have been recommended for fixing guided bone regeneration (GBR) membranes and stabilizing the graft. However, the removal of fixation screws or pins often requires an additional surgical procedure. This article presents a periosteal suturing technique with resorbable sutures for the fixation of grafts and membranes in GBR in single implant s...