نتایج جستجو برای: brain extract
تعداد نتایج: 644973 فیلتر نتایج به سال:
OBJECTIVES The present study was undertaken to investigate the effect of the ethanolic extract of Allium sativum L. (Family: Lilliaceae), commonly known as garlic, on depression in mice. MATERIALS AND METHODS Ethanolic extract of garlic (25, 50 and 100 mg/kg) was administered orally for 14 successive days to young Swiss albino mice of either sex and antidepressant-like activity was evaluated ...
candida species are the most common cause of opportunistic fungal infection worldwide. due to increasing resistance of fungi against conventional drugs, as well as their side effects, alternative natural products have become a renewed interest. in the current study, the anti-candida activities of scrophularia striata extract were examined. in this experimental study, microdilution assay and wel...
The aim of this study was to examine the effect of a polyphenol-rich extract (PrB) of Vaccinium angustifolium (wild blueberries) introduced intraperitoneally (i.p.) at 30 (PrB30) and 60 (PrB60) mg/kg body weight for 7 days, on cognitive performance, brain oxidative status and acetylcholinesterase activity in adult, male, 3-4-month-old Balb-c mice. Evaluation of rodent learning and memory was as...
Background and Objective: Alzheimer’s disease (AD) is a degenerative disorder that leads to progressive cognitive decline. The memory dysfunction of AD has been associated with a cortical cholinergic deficiency and loss of cholinergic neurons of the nucleus basalis of Meynert (NBM). This study investigated the effect of ethanolic extract of Cyperus rotundu tubers (CRT) on motor activity in NBM-...
Background and purpose: The use of an appropriate stimulus for increasing the rate of neural stem cell proliferation is one of the most important issues in cell therapy. This study aimed to investigate the effect of hydroethanolic extract of Stachys byzantina on hippocampus-derived neural stem cell proliferation and apoptosis. Materials and methods: In this experimental study, the neural ste...
Background: Parkinson's disease is one of the prevalent degenerative diseases of the neural system. Oxidative stress, which has been recognized as the most important factor of Parkinson's disease, plays a main role in the death of neurons in this disease. Antioxidants have a proved role in the prevention of oxidative stress. Objective: Considering the presence of evidence regarding antioxid...
Background: Olive has a protective effect against chronic inflammatory conditions. However, it is not clear weather this effect is due to its immunomodulatory or antioxidant property. The aim of this study was to investigate the effect of olive leaf extract on serum levels of Th-17 related cytokines and its antioxidant properties. Materials and Methods: 40 male rats divided into 5 groups, and w...
BACKGROUND The present investigation deals with the assessment of neuroprotective effect Amorphophallus campanulatus (AC) tuber in alzheimer diseased (AD) rat and also postulates its possible mechanism of action. MATERIAL AND METHODS AD was induced by administering streptozotocin i.e. STZ (3 mg/kg, ICV) day one and 3rd day after surgery. Surgery was performed on anesthetized rats by the help ...
The aim of this study was to investigate the protective role of red grape seed extracts (GSEs) against oxidative damage on DNA, brain and erythrocytes in vitro. In this study, the protective effects of two GSEs (water and ethanol) on free radical mediated DNA-sugar damage, Fe -induced lipid peroxidation in brain and 2+ H O induced hemolysis and lipid peroxidation of erythrocytes were determined...
Expression of myelin basic protein (MBP) in mice is regulated in a cell- and stage-specific manner during brain development. The MBP control region contains multiple cis-acting elements, shown by in vivo and in vitro assays, which are responsible for its unique pattern of transcription. Using synthetic DNA fragments spanning the MBP control region, we have analyzed nuclear proteins obtained fro...
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