Hydroxyapatite (HA), a material proven to be biocompatible within the human body, has been produced to a high level of purity. This material has been applied as a coating on Ti-6Al-4V alloy by using the air plasma spraying technique. The coat was characterizted with SEM, XRD, FTIR and Raman spectroscopy methods to consist of a mixture of calcium phosphates including HA mainly and traces of tric...

This paper presents a simple method for the rapid synthesis of magnetite/hydroxyapatite composite particles. In this method, superparamagnetic magnetite nanoparticles are first synthesized by coprecipitation using ferrous chloride and ferric chloride. Immediately following the synthesis, carbonate-substituted (B-type) hydroxyapatite particles are mechanochemically synthesized by wet milling dic...

OBJECTIVE To detect the hydroxyapatite component of vascular calcification in vivo so that the process of calcium deposition can be studied in transgenic model systems. METHODS AND RESULTS We have previously developed a near-infrared fluorescent bisphosphonate derivative that binds with high affinity and specificity to hydroxyapatite, and an intraoperative near-infrared fluorescence imaging s...

Tissue engineering using living cells is emerging as an alternative to tissue or organ transplantation. The adult mesenchymal stem cells can be differentiated into multilineage cells, such as adipocytes, chondrocytes, or osteoblasts when cultured with specific growth factors. In the present investigation, we have studied the effect of honeycomb collagen scaffolds for the adhesion, differentiati...

Model compounds which resemble the calcium phosphates deposited in biological systems have been synthesised, characterised by a variety of physical techniques and their EXAFS spectra recolded abo~c, the calcium K edge. The spectrum of one of the compounds, hydroxyapatite, has been ;in:~iysecl and the results used to aid the analysis of spectra from related compounds. Spectra recorded above the ...

Hydroxyapatite, the main mineral phase of mammalian tooth enamel and bone, grows within nanoconfined environments and in contact with aqueous solutions that are rich in ions. Hydroxyapatite nanopores of different pore sizes (20 Å ≤ H ≤ 110 Å, where H is the size of the nanopore) in contact with liquid water and aqueous electrolyte solutions (CaCl2 (aq) and CaF2 (aq)) were investigated using mol...

PURPOSE To report the long-term results of orbital volume augmentation using calcium hydroxyapatite filler injections in patients with anophthalmic sockets. METHODS Twelve eligible patients with post-enucleation socket syndrome (PESS) and small orbital volumes were included in our study. In this investigation, 1.5 mL injectable calcium hydroxyapatite (Radiesse) was utilized in an off-label ap...

Crystal growth in native collagen gels has been used to determine the role of extracellular matrix macromolecules in biological calcification phenomena. In this system, type I collagen gels containing sodium phosphate and buffered at pH 7.4 are overlayed with a solution containing CaCl2. Crystals form in the collagen gel adjacent to the gel-solution interface. Conditions were determined which p...

A mechanism of the transport of nanocrystalline doped calcium carbonatephosphates through the membrane on the model of interaction with phospholipids is considered. Nanocrystalline doped calcium carbonate – phosphates are perspective to transport of the cations in a living cell. Kinetics of the synthesis of nanocrystalline doped calcium carbonatephosphates are non-linear kinetics. Biomaterial b...

Synthetic apatites are widely used both in the dental and the orthopaedic fields due to their similarity in composition with the inorganic phase of hard tissues. Biologic apatites are not pure hydroxyapatite (HA), but are calcium-deficient apatites with magnesium and carbonate as minor but important substituents. The aim of the present study was to produce a more soluble biomaterial through the...