Stromal cells such as myofibroblasts influence tumor progression. The mechanisms are unclear but may involve effects on both tumor cells and recruitment of bone marrow-derived mesenchymal stromal cells (MSCs) which then colonize tumors. Using iTRAQ and LC-MS/MS we identified the adipokine, chemerin, as overexpressed in esophageal squamous cancer associated myofibroblasts (CAMs) compared with ad...

This licentiate thesis work investigates two medium access control (MAC) methods, when used in traffic safety applications over vehicular ad hoc networks (VANETs). The MAC methods are carrier sense multiple access (CSMA), as specified by the leading standard for VANETs IEEE 802.11p, and self-organizing time-division multiple access (STDMA) as used by the leading standard for transponders on shi...

Abstract Collaborative robots must simultaneously be safe enough to operate in close proximity human operators and powerful assist users industrial tasks such as lifting heavy equipment. The requirement for safety necessitates that collaborative are designed with low-powered actuators. However, some may require the robot have high payload capacity and/or long reach. For designs successful, they...

Background Patient’s rights are worldwide considerations. Saudi Patient’s Bill of Rights (PBR) which was established in 2006 contained 12 items. Lack of knowledge regarding the Saudi PBR limits its implementation in health facilities. This study aimed to investigate the knowledge of health professions’ students at College of Applied Medical Sciences (CAMS) Riyadh Saudi Arabia regarding the exis...

To identify the molecules on the neuronal surface that mediate axonal growth on myotubes, we have examined neurite formation by ciliary neurons grown on myotubes in the absence or presence of specific antibodies. Dramatic inhibition of neurite outgrowth was seen only when antibodies blocked simultaneously the functions of two cell adhesion molecules--neural cell adhesion molecule (N-CAM) and ne...

BACKGROUND The aim of this study was to explore the biomarkers and potential mechanism underlying ischemic cardiomyopathy (ICM). METHODS Using the GSE42955 Affymetrix microarray data accessible from the Gene Expression Omnibus database, the differentially expressed genes between 12 ICM tissue samples and 5 normal controls were identified. To investigate the function changes in the course of d...

OBJECTIVES The present study examined the association of estrogen (E2) and the inflammatory response of endothelium in coronary artery disease (CAD) by measuring circulating cellular adhesion molecules (cCAMs) in subjects with atherosclerosis. BACKGROUND Atherosclerotic plaque demonstrates features similar to inflammation. Endothelial cell activation by inflammatory cytokines induces expressi...

A proper balance between cell adhesion and repulsion is essential for cellular morphogenesis during epithelial-mesenchymal transition and mesenchymal-epithelial transition. A number of ligand-receptor pairs including hepatocyte growth factor/scatter factor-Met and semaphorin-plexin are known to control this balance through the complex intracellular signaling pathways. Cell adhesion to other cel...