نتایج جستجو برای: cancer activity
تعداد نتایج: 1961890 فیلتر نتایج به سال:
Background and objectives: Beside its nutritional role, caper (Capparis spinosa) has long been used as an analgesic, anti-inflammatory, anti-diabetic and anti-cancer remedy. In the present study, we tested whether this plant can make effective changes in Sirt3 and mitochondrial function in colorectal carcinoma cell line since mitochondrial dysfunction has long been imp...
Objective(s): Chalcones and their rigid analogues represent an important class of small molecules having anticancer activities. Therefore, in this study the synthesis and cytotoxic activity of new 3-benzylidenchroman-4-ones were described as rigid chalcone analogues. Materials and Methods: The reaction of resorcinol with 3-chloropropionic acid in the presence of CF3SO3H was a...
Background and purpose: Bleomycin as an anticancer drug causes side effects on normal tissues. The aim of this study was to investigate the effect of methanolic extract of Cichorium intybus seed (CI) on antiproliferative activity of bleomycin on human non-malignant skin and ovarian cancer cells. Materials and methods: Human non-malignant fibroblast cells (HFFF2) and ovarian cancer cells (SKOV-...
Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...
Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...
Cancer is not just one disease, but a large group of almost one hundred diseases. Its two main characteristics are uncontrolled growth of the cells in the human body and the ability of these cells to migrate from the original site and spread to distant sites. If the spread is not controlled, cancer can result in death. There has been continuous progress in the development of therapy for cancer....
Background: Breast cancer is one of the most prevalent cancers among women and features increasing trends of incidence rates. Worldwide, yearly about 1.67 million of new cases and 522,000 of deaths from breast cancer are registered. The aim of this study was to determine the risk factors of breast cancer in women and to identify high risk groups. Methods: In a case-control study, 170 women w...
Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...
introduction: endothelial progenitor colony forming unit-endothelial cells (cfu-ec) were first believed to be the progenitors of endothelial cells, named endothelial progenitor cells. further studies revealed that they are monocytes regulating vasculogenesis. the main hindrance of these cells for therapeutic purposes is their low frequency and limited replicative potentials. this study was unde...
abstract anthocyanins are natural pigments widely spread in nature. anthocyanin color molecules are a subclass of flavonoids. they are responsible for red, purple, and blue colors of many flowers, fruits and vegetables. fruits and berries are sample sources of anthocyanins in nature. in many researches, the positive effects of fruits and berries intake on human health have been reported. anth...
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