The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with variety of human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In 2004, EBV was described as one first known oncoviruses to encode viral microRNAs (miRNAs), these molecules were found interact host targets. miRNAs modulate biological processes that are critical for carcinogenesis, contributing cell t...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue. Moreover, among these factors, infection and its association to cancers is controversial. Although, it seems that the genome instability of the cells can initiate cancer development. The purpose of this review...

worldwide, thyroid cancers are the most common type of endocrine-related cancers. papillary carcinoma accounts for the most frequent type of thyroid malignancy. a rare variant of papillary carcinoma of the thyroid is the cribriform-morular variant. we report a case of solitary, cribriform-morularvariant of papillary carcinoma in a 55-year-old lady. it is important to identify this variant becau...

abstract bachground and aim: mutation analysis of mitochondrial genome and brca genes are helpful in the early diagnosis of familial breast cancers. in this study, we investigated mitochondrial common deletion and brca mutations through multiplex pcr and clinical parameters for the detection of familial breast cancers in archival breast cancer samples. methods: the multiplex pcr was conducted o...

background: cancer is the second most common cause of non-accidental death in iran. geographical, racial and habitual differences have led to the variation in the incidence of cancer in different regions of this country. this study was performed to determine the incidence of cancer in the kerman province, central iran. methods: all newly diagnosed cases of cancer in the kerman province were rec...

Background Ovarian tissue cryopreservation is an option for patients who require immediate gonagonadotoxic treatment of cancers. when there is insufficient time to conduct ovulation induction This procedure can be used in patients with genetic mutations with a high risk for premature ovarian failure.This strategy is the only option for fertility preservation in prepubertal girls or in women who...