because of antimicrobial, antioxidant, and anticancer potential, salvia chorassanica bunge (lamiaceae) has been considered as a popular herb in iranian traditional medicine. previous studies have shown remarkable cytotoxic properties of the methanol, n -hexane and dichloromethane extract of s. chorassanica on human cervical cancer cells. to seek the therapeutic potentials of s. chorassanica, th...

Background: Lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (NSCLC). For therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. Objective: To charac-terize a murine monoclonal antibody (ME3D11) reactive with human NSCLC. Methods: A murine monoclonal antibody (ME3D11) reactive with human NSCLC was s...

the objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of cucumis melo in human prostate cancer cell line (pc-3) using mttand neutral red assays. the crude aqueous extract of c.melo was prepared by cold maceration method, filtered,concentrated and tested on pc-3 cell line. dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma pc-3 cell l...

euphorbia wallichii a perennial herb growing mainly in himalayas has been widely used in folk medicines for its medicinal properties. in the present study, the crude methanolic root extract (cme) and its fractions; n-hexane fraction (nhf), n-butanol fraction (nbf), chloroform fraction (chf), ethyl acetate fraction (eaf) and aqueous fraction (aqf) of this plant specie were investigated for antio...

background: cirrhinus mrigala, one of the important fish widely consumed in india, was used for karyological observations and to evaluate the toxic effect of butachlor, an extensively used herbicide in rice fields in terms of chromosomal aberration test. methods: fishes were collected from “national fish seed farm” jyotisar with mean body weight of 20-50g. the experimental fishes were kept in t...

breast cancer is the second main cause of death among women. the use of medicinal plants has been common in many countries since ancient times. the aim of this study was to evaluate the antioxidant and anti-proliferative potential of achillea millefolium l. the antioxidant activity of the aqueous and hydroalcoholic extracts of achillea millefolium l. leaf and flower was measured by dpph and fra...

background: the monoclonal antibody, c595, against breast cancer cell line was conjugated with cyclic anhydride gadolinium-diethylenetriaminepenta-acetic acid (gd-cdtpaa) to produce gd-dtpa-c595 and used as specific breast cancer cell line (mcf-7) contrast agents in magnetic resonance imaging (mri).  methods: after incubation of breast cancer cell line (mcf-7), with different contrast agents (g...

background: lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (nsclc). for therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. objective: to charac-terize a murine monoclonal antibody (me3d11) reactive with human nsclc. methods: a murine monoclonal antibody (me3d11) reactive with human nsclc was s...