This study investigates the antibacterial mechanism of action of electrospun chitosan-based nanofibers (CNFs), against Escherichia coli, Salmonella enterica serovar Typhimurium, Staphylococcus aureus and Listeria innocua, bacteria frequently involved in food contamination and spoilage. CNFs were prepared by electrospinning of chitosan and poly(ethylene oxide) (PEO) blends. The in vitro antibact...

INTRODUCTION This study describes the results achieved using a combination of allogeneic mesenchymal stem cells (MSCs) with chondrocytes (CHC) and a new scaffold consisting of type-I collagen and chitosan nanofibers in the prevention of partial growth plate arrest after iatrogenic injury in pigs. MATERIAL AND METHODS The miniature pig was selected as an experimental model to compare the resul...

In this research, a novel fixed-bed reactor was designed with a nanofiber membrane composed of a polyvinyl alcohol (PVA)/chitosan nanofiber blend prepared using an electrospinning technique. The applied voltage, tip-collector distance, and solution flow rate of the electrospinning process were 18 kV, 14.5 cm, and 0.5 mL h(-1), respectively. Brunauer-Emmett-Teller (BET) theory, scanning electron...

Chitosan (CS) is a natural biopolymer that due to its excellent properties such as biocompatibility and biodegradability suitable for use in many applications. But, dependent on the molecular weight other electrospinning capability of CS very weak. To solve this problem, it recommended blend with second polymer. In work, CS/polyamide-6 (PA6) composite nanofibers were fabricated by technique. Th...

The biopharmaceutical industry has a growing demand and an increasing need to improve the current virus purification technologies, especially as more and more vaccines are produced from cell-culture derived virus particles. Downstream purification strategies can be expensive and account for 70% of the overall manufacturing costs. The economic pressure and purification processes can be particula...

The development and utilization of three-dimensional cell culture platforms has been gaining more traction. Three-dimensional culture platforms are capable of mimicking in vivo microenvironments, which provide greater physiological relevance in comparison to conventional two-dimensional cultures. The majority of three-dimensional culture platforms are challenged by the lack of cell attachment, ...

electrospinning was applied to nitrocellulose (nc) solutions  in dmf, dmso  and  ethyl  methyl  keton  to  obtain  nc  nanofibers. electrospraying  process  was  observed  when  dmf  was  used  as solvent.  in  comparison  to nc/dmf, nc/dmso  solution  resulted  in the  formation  of  a  coating  film  as  indicate  by  sem.  two  different electrospun  nanofibers,  smooth  nanofibers  with  90...

Objective(s): Polymeric nanofiber has a huge potential for a various biomedical applications such as wound healing and orthopedic implant. Since most of the future applications of therapeutic nanofiber are interacting with human blood components, it is important to investigate hemocompatibility. Methods: In this study, nanofibers with antibacterial properties were synthesizedby elec...

The principal intention of this work is to fabricate and characterize the polyamide/chitosan nanocomposite by a novel single solvent method through electrospinning procedure. thermal properties morphology prepared are studied thermogravimetric analysis (TGA) field-emission scanning electron microscopy (FE-SEM). TGA exposed that primary decomposition temperature reduced with rising chitosan cont...