نتایج جستجو برای: clinical trial study

تعداد نتایج: 4832894  

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده علوم پزشکی 1389

هدف: در این مطالعه به بررسی اثرات داروی میتومایسین c در جلوگیری از به وجود آمدن چسبندگی های بعد از عمل جراحی و اندوسکوپی بینی و سینوس در بیمارستان بوعلی طی سال 89 پرداختیم.روش مطالعه: این مطالعه به صورت یک بررسی مداخله ای (interventional) از نوع کارآزمایی بالینی تصادفی (randomized clinical trial) انجام گردیده است. جامعه مورد بررسی شامل 63 نفر (126 سوراخ بینی) از افراد تحت عمل جراحی و اندوسکوپی ...

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده علوم پزشکی 1389

در این مطالعه به بررسی تغییرات همودینامیک ناشی از مصرف رمی فنتانیل بعلاوه پروپوفول در قیاس با رمی فنتانیل بعلاوه ایزوفلوران در بیماران تحت جراحی اندوسکوپیک سینوس در بیمارستان های آموزشی دانشگاه آزاد در سال 1389 پرداختیم.روش مطالعه: این مطالعه به صورت یک بررسی مداخله ای (interventional) از نوع کارآزمایی بالینی تصادفی (randomized clinical trial) انجام شده است. 96 بیمار به صورت تصادفی در یکی از دو...

2013
An-Wen Chan Jennifer M Tetzlaff Peter C Gøtzsche Douglas G Altman Howard Mann Jesse A Berlin Kay Dickersin Asbjørn Hróbjartsson Kenneth F Schulz Wendy R Parulekar Karmela Krleža-Jerić Andreas Laupacis David Moher

High quality protocols facilitate proper conduct, reporting, and external review of clinical trials. However, the completeness of trial protocols is often inadequate. To help improve the content and quality of protocols, an international group of stakeholders developed the SPIRIT 2013 Statement (Standard Protocol Items: Recommendations for Interventional Trials). The SPIRIT Statement provides g...

Journal: :Biometrics 1996
S Murray A A Tsiatis

One of the primary problems facing statisticians who work with survival data is the loss of information that occurs with right-censored data. This research considers trying to recover some of this endpoint information through the use of a prognostic covariate which is measured on each individual. We begin by defining a survival estimate which uses time-dependent covariates to more precisely get...

Journal: :Biostatistics 2000
S R Lipsitz J G Ibrahim

Incomplete covariate data are a common occurrence in studies in which the outcome is survival time. Further, studies in the health sciences often give rise to correlated, possibly censored, survival data. With no missing covariate data, if the marginal distributions of the correlated survival times follow a given parametric model, then the estimates using the maximum likelihood estimating equat...

Journal: :Biometrics 1999
B K Mallick D G Denison A F Smith

A Bayesian multivariate adaptive regression spline fitting approach is used to model univariate and multivariate survival data with censoring. The possible models contain the proportional hazards model as a subclass and automatically detect departures from this. A reversible jump Markov chain Monte Carlo algorithm is described to obtain the estimate of the hazard function as well as the surviva...

Journal: :Pediatrics 2013
Alan E Simon Anne Driscoll Yelena Gorina Jennifer D Parker Kenneth C Schoendorf

BACKGROUND Although national cross-sectional estimates of the percentage of children enrolled in Medicaid are available, the percentage of children enrolled in Medicaid over longer periods of time is unknown. Also, the percentage and characteristics of children who rely on Medicaid throughout childhood, rather than transiently, are unknown. METHODS We performed a longitudinal examination of M...

Journal: :Biometrics 1999
S Murray A A Tsiatis

This research develops nonparametric strategies for sequentially monitoring clinical trial data where detecting years of life saved is of interest. The recommended test statistic looks at integrated differences in survival estimates during the time frame of interest. In many practical situations, the test statistic presented has an independent increments covariance structure. Hence, with little...

Journal: :Annali di igiene : medicina preventiva e di comunita 2017
L Capasso M Gaeta L Appolloni D D'Alessandro

In the past decades, Italian hygienic requirements for dwellings have been modified by multiple derogations. Aim of the present work is to analyse the derogations introduced at a national, regional, and local level. The most important derogations were related to the habitable use of semi-basements and garrets, and building restoration. The paper also describes the regulations regarding indemnit...

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