This study aimed to investigate the cardiovascular effects elicited by Dictyota pulchella, a brown alga, using in vivo and in vitro approaches. In normotensive conscious rats, CH(2)Cl(2)/MeOH Extract (CME, 5, 10, 20 and 40 mg/kg) from Dictyota pulchella produced dose-dependent hypotension (-4 ± 1; -8 ± 2; -53 ± 8 and -63 ± 3 mmHg) and bradycardia (-8 ± 6; -17 ± 11; -257 ± 36 and -285 ± 27 b.p.m...

The onset times and peak intensities of solar energetic particle (SEP) events at Earth have long been thought to be influenced by the open magnetic fields of coronal holes (CHs). The original idea was that a CH lying between the solar SEP source region and the magnetic footpoint of the 1 AU observer would result in a delay in onset and/or a decrease in the peak intensity of that SEP event. Rece...

We devise a test of the chiral magnetic and chiral vortical effects (CME and CVE) in relativistic heavy ion collisions that relies only on the general properties of triangle anomalies. We show that the ratio R(EB) = J(E)/J(B) of charge J(E) and baryon J(B) currents for CME is R(EB)(CME) → ∞ for three light flavors of quarks (N(f) = 3), and R(EB)(CME) = 5 for N(f) = 2, whereas for CVE it is R(EB...

We describe a new modeling approach to develop a more quantitative understanding of the charge state distributions of the ions of various elements detected in situ during halo Coronal Mass Ejection (CME) events by the Advanced Composition Explorer (ACE) satellite. Using a model CME hydrodynamic evolution based on observations of CMEs propagating in the plane of the sky and on theoretical models...

The head, face, masticatory sytem, and cervical region are common sites in which pain is experienced. Many conditions present with similar signs and characteristic patterns that may lead to diagnostic confusion and ultimately misdirected care. Defined, validated classification systems relating to the multiplicity of painful entities can simplify and enhance diagnostic outcomes. Due to the rapid...

Regular readers of P&T understand that we are facing a crisis in continuing medical education (CME). This situation has its roots in multiple areas, including a history of financial abuses, congressional interests in these abuses, and a growing awareness that traditional clinical CME simply does not change clinician behavior. More frequently, we are hearing stories about academic medical center...

The severe geomagnetic effects of solar storms or coronal mass ejections (CMEs) are to a large degree determined by their propagation direction with respect to Earth. There is a lack of understanding of the processes that determine their non-radial propagation. Here we present a synthesis of data from seven different space missions of a fast CME, which originated in an active region near the di...

Clathrin-mediated endocytosis (CME) involves the recruitment of numerous proteins to sites on the plasma membrane with prescribed timing to mediate specific stages of the process. However, how choreographed recruitment and function of specific proteins during CME is achieved remains unclear. Using genome editing to express fluorescent fusion proteins at native levels and live-cell imaging with ...

FULL DISCLOSURE POLICY In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a f...

FULL DISCLOSURE POLICY In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a f...