application of therapeutic gene transfer in the treatment of genetic diseases is a notable progress but there are some disadvantages and limitations in it. the process of overcoming these barriers is a drastic change in gene delivery. recently, calcium phosphate nanoparticles alone, or in combination with viral and nonviral vectors, were found to have a positive effect on gene transfer especial...

We report the synthesis of colloidal CdSe quantum dots doped with a novel Ag precursor: AgCl. The addition of AgCl causes dramatic changes in the morphology of synthesized nanocrystals from spherical nanoparticles to tetrapods and finally to large ellipsoidal nanoparticles. Ellipsoidal nanoparticles possess an intensive near-IR photoluminescence ranging up to 0.9 eV (ca. 1400 nm). In this artic...

X-Ray photoelectron spectroscopy has been extended to colloidal nanoparticles in aqueous solution using a liquid microjet in combination with synchrotron radiation, which allowed for depth-dependent measurements. Two distinct electronic structures are evident in the Si 2p photoelectron spectrum of 7 nm SiO(2)-nanoparticles at pH 10. A core-shell model is proposed where only the outermost layer ...

Freeze-drying has been considered as a good technique to improve the long-term stability of colloidal nanoparticles. The poor stability in an aqueous medium of these systems forms a real barrier against the clinical use of nanoparticles. This article reviews the state of the art of freeze-drying nanoparticles. It discusses the most important parameters that influence the success of freeze-dryin...

in study, spherical silver nanoparticles (snps) were synthesized by chemical reduction method from a metal precursor silver nitrate in presence of an anionic surfactant and strong reducing agent. in this experimental work, snps are synthesized in presence of different concentration of stabilizing agent and effect of stabilizing agent on size distribution of snps have been observed. further anti...

This review covers the emerging field of nanobiotechnology, in which nanoparticles are applied to the analysis of biomolecules. Nanoparticles can be used in a variety of bioanalytical formats, and this review discusses four classes of use. First, nanoparticles as quantitation tags, such as the optical detection of quantum dots and the electrochemical detection of metallic nanoparticles. Second,...

Composite hydrogels were prepared that consisted of quasi-colloidal layered double hydroxide (LDH) nanoparticles and agarose via the electrophoretic method, starting from three different agarose concentrations of 0.5, 1, and 2 wt/v%. The composite hydrogel was identified to have a uniform distribution of LDH nanoparticles in agarose matrix. Microscopic studies revealed that the composite hydrog...

Colloidal Cu@CuAlO(2)-Al(2)O(3) bimetallic nanoparticles were prepared by a gamma irradiation method in an aqueous system in the presence of polyvinyl pyrrolidone (PVP) and isopropanol respectively as a colloidal stabilizer and scavenger of hydrogen and hydroxyl radicals. The gamma irradiation was carried out in a (60)Co gamma source chamber with different doses up to 120 kGy. The formation of ...

A novel confined-space synthesis method has been developed to synthesize zeolite nanocrystals. Colloidal silica nanoparticles serving as the silica source as well as the hard template were embedded in the mesoporous carbon via in situ polymerization of furfuryl alcohol (FA) in the presence of tri-block copolymer (Pluronic P123), and then reacted with an alkaline aqueous solution (Na2O-Al2O3-H2O...