PurposeThe ‘chapeau de gendarme’ (CDG) sign, characterised by a symmetric down-turned mouth, has been considered as semiological hallmark of focal epileptic seizures with cingulate or insular involvement. We report three cases in which the CDG sign featured habitual seizures.MethodsThe epileptogenic zones these patients were localized lateral prefrontal cortex video-stereoelectroencephalography...

Abstract Recent studies have identified two distinct cortical representations of voice control in humans, the ventral and dorsal laryngeal motor cortex. Strikingly, while persistent developmental stuttering has been linked to a white-matter deficit cortex, intensive fluency-shaping intervention modulated functional connectivity network. Currently, it is unknown whether underlying structural net...

Motor imagery is defined as an act wherein individual contemplates a mental action of motor execution without apparent action. Mental practice executed by repetitive can improve performance simultaneous sensory input or overt output. We aimed to investigate cerebral hemodynamics during and self-feeding activity using chopsticks. This study included 21 healthy right-handed volunteers. The task c...

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introduction: (s)- 3,5-dihydroxyphenylglycine (dhpg) is an agonist for group i metabotropic glutamate receptors. dhpg-induced synaptic depression of excitatory synapses on hippocampal pyramidal neurons is well known model for synaptic plasticity studies. the aim of the present study was to examine the effects of dhpg superfusion on excitatory synapses on pyramidal and fast-spiking gabaergic cel...

objective(s): the present study investigated the effects of microinjection of histamine and histamine h1, h2, and h3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (psc) on inflammatory pain.   material and methods: two stainless steel guide canulas were bilaterally implanted into the psc of anaesthetized rats. inflammator...

introduction: the current study aimed to elucidate the role of preparatory cognitive control in decision making and its neural correlates using functional magnetic resonance imaging (fmri). to this effect, by employing a series of new cognitive tasks, we assessed the role of preparatory cognitive control in monetary (risky) decision making. methods: the participants had to decide between a risk...

The analysis of evoked potentials of sensorimotor cortex in response to electrical stimulation of n. ischiadicus shows that the extremal factor hypokinesia has a negative impact on the dynamics of formation of amplitudal and temporal characteristics since eyes openning in 2-weeks old rats. The most vulnerable process to the impact of hypokinesia is the first-positive phase, which disappears in ...

In this study, the effect of topiramate, as an antiepileptic drug, was evaluated on morphine craving in rats. The conditioned place preference (CPP) test was used for this purpose. Repeated administration of morphine (10 mg/kg, i.p. for 4 days) induced significant CPP. Administration of topiramate (50 and 100 mg/kg, i.p. for 4 days) with each morphine administration decreased the acquisition of...