Kunyit hitam ( Curcuma caesia Roxb.) memiliki aktivitas farmakologi serta dimanfaatkan sebagai obat tradisional untuk menyembuhkan berbagai penyakit dengan pemanfaatan rhizoma, akar, dan daun. Penelitian ulasan artikel ini bertujuan mengetahui manfaat kunyit sehingga dapat diharapkan salah satu bahan alami sekaligus meningkatkan potensi ekonomi masyarakat melalui budidaya pertanian yang dirinti...

The sesquiterpenoids are one of major groups of antioxidants in Curcuma besides curcuminoids. However, the real substances contributing to the antioxidant activity are still unknown. In this paper, the antioxidant activity of sesquiterpenoids in four species and two essential oils from Curcuma genus was determined and compared based on TLC separation and DPPH bioautography assay. Their antioxid...

Jun/Fos, a crucial factor in transmitting the tumor-promoting signal from the extracellular environment to the nuclear transcription machinery, has a dimerization interface possessing several coiled structural properties. Jun and Fos can interact with the DNA regulatory region, AP-1 (Activator Protein-1), which is composed of 5'-TGAC/GTCA-3'. Curcumin is a well-known anticancer and anti-inflamm...

Curcuma longa is widely known for its anti-inflammatory activity in traditional system of medicine for centuries and has been scientifically validated extensively. The present study was conducted to evaluate the anti-inflammatory activity of curcuminoids and oil-free aqueous extract (COFAE) of C. longa and compare it with that of curcuminoids and turmerones (volatile oil), the bioactive compone...