dendritic cells (dcs) induce pathogen-specific t cell responses. we comprehensively studied the effects of addition of maturation stimulus, fibroblasts (fibroblast conditioned medium), pha activated t cells (t cell conditioned medium), and mixture of fibroblast & pha activated t cells (fcm-tccm) conditioned media on maturation of dcs. monocytes were cultured with gm-csf and il-4 for five da...

Background: Pemphigus vulgaris (PV) is an autoimmune bullous disorder that is fatal if left untreated. High dose systemic corticosteroids are the basis of therapy. The addition of immunosuppressive agents has improved the disease outcome and reduced the required corticosteroid dose and related toxicity. Mycophenolate mofetil is increasingly used as a steroid-sparing agent in immunotherapy of PV...

background: the aim of this study was to examine the renoprotective effect of hydro alcoholic sage (salvia officinalis: so) leaves extract against gentamicin-induced nephrotoxicity in rats. methods: in this experimental study forty male sprague dawley rats weighing 200-300 g were randomly divided into 5 groups; (1) the rats without treatment (control), (2) intraperitoneally injected with normal...

objective(s):the purpose of the present study was to investigate the protective effect of oxytocin on cisplatin (cp)-induced renal damage in rats. materials and methods: fourteen adult sprague dawley rats, weighing 200 to 210, were administered by cisplatin (cp, 2 mg/kg/day) twice a week for five weeks. then, they were randomly divided into two groups and treated with either saline (1 ml/kg/day...