OBJECTIVE To determine the prevalence of cutaneous anergy in pregnant and nonpregnant women who are seropositive for human immunodeficiency virus. METHODS AND MATERIALS The medical records of 159 women seropositive for human immunodeficiency virus were reviewed. Demographic characteristics and tuberculin skin test results were abstracted from the chart. Tuberculin skin testing was performed b...

Congratulations on the publication of the ‘‘Tuberculosis in NSW’’ edition (2013; 24(1)). It makes excellent reading on a disease that continues to smoulder in this country. However, there is one topic on which some authors appear unclear: the limitations of immunological tests for both tuberculosis (TB) disease and infection. I refer to the tuberculin skin test (TST) and interferon-gamma releas...

, 81 infliximab naive RA patients and 47 healthy subjects as controls. At the same time and apart from the purposes of that study, we also had done a pathergy test in those subjects who agreed to participate, with the aim of determining the effect of the pathergy phenomenon on the response of BS patients to the tuberculin test. Informed consent was obtained from all subjects. The study was appr...

he marked annual decrease in the number of Tnewly reported cases of active tuberculosis during the past ten years has been accompanied by a similar decreased effectiveness of chest x-ray mass screening as a tool in community tuberculosis casefinding programs. However, during the same period, tuberculin skin testing of pre-school and school age children, followed by a thorough examination of pos...

In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sites caused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune respon...

SETTING Six selected districts in Northern India. OBJECTIVES To find out the trend in Annual risk of tuberculous infection (ARTI) in north India. STUDY DESIGN Two rounds of community level surveys were conducted during 2000-2001 and 2009-10 respectively. Representative samples of children 1-9 years of age were tuberculin tested and maximum transverse diameter of induration was recorded in m...

Anal strictures with fibrotic induration have been shown to develop in up to 50% of all patients with Crohn's disease (CD) with anal ulceration. We evaluate the technical feasibility, safety and long-term efficacy of bougie dilation for a subgroup of patients with symptomatic Crohn's-related fibrotic anal strictures. Bougie dilation is simple to perform, relatively inexpensive and has a low ris...

A case of sarcoidosis, unusual in that it was confined to the tongue, is reported in a 50 year-old female. The condition resolved after 1 year of steroid therapy and excision of fibrous tethering bands. Intra-oral sarcoidosis should be considered in the differential diagnosis of lingual swelling and induration.

The allergic reactions of dermal induration and hyperthermia were compared in tuberculin-hypersensitive calves. Tuberculins prepared from Mycobacterium avium, M. bovis, and M. paratuberculosis were administered intradermally and the responses were compared. The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared...