In this paper, we focus on outsourcing activities optimization problem in single period setting. In some situations, capacity planning or outsourcing is a one-time event and can be modeled as a single period problem. The aim of this research is to balance the trade-off between two echelons of a supply chain consisting of a single outsourcer and a single subcontractor. Each part is composed of a...

We present a novel simulation platform called Optimization, Simulation, and Forecasting (OSF) for the domain of manufacturing and logistics supply-chain systems. It supports composition of DEVS, Linear Program (LP), and forecast models using an extended Knowledge Interchange Broker (KIB). Models developed in DEVS-Suite simulator, OPL-Studio optimization, and a heuristic Inventory Strategy Forec...

Operations Research has addressed a variety of environmental problems outside the traditional supply chain management area such as remanufacturing, reverse logistics, and waste management. Supply chain sustainability, which includes designing green supply chains, will gain much more attention in the future. Indeed, most companies are still in the early stage of considering a green initiative. T...

In the pharmaceutical industry, the development activities that are required to bring a new drug to market involve considerable expense (upwards of $1 Billion) and can take in excess of 10 years. Clinical trials constitute a critically important and very expensive part of this development process as the associated supply chain encompasses producing, distributing and administering the candidate ...

In today’s global marketplace, individual firms do not compete as independent entities rather as an integral part of a supply chain. This paper proposes a fuzzy mathematical programming model for supply chain planning which considers supply, demand and process uncertainties. The model has been formulated as a fuzzy mixed-integer linear programming model where data are ill-known andmodelled by t...

it is necessary to consider the impact of demand uncertainty to model the comprehensive approach for supply chain network design. this paper presents four echelons, multiple commodity, and strategic–tactical model for designing supply chain network. uncertain demand, transportation mode selection with lead time configuration has been considered. a numerical example has been implemented to verif...