Insect vectors and insect-borne plant viruses seriously endanger the safety of agricultural production. An insecticide is one main methods to prevent virus transmission. However, curious relationship between resistance insect arboviruses has been less studied. In this study, effect Tomato chlorosis (ToCV) on Bemisia tabaci MED was It found that detoxification cytochrome P450, glutathione S-tran...

Living organisms, from bacteria to humans, display a coordinated transcriptional response to xenobiotic exposure, inducing enzymes and transporters that facilitate detoxification. Several transcription factors have been identified in vertebrates that contribute to this regulatory response. In contrast, little is known about this pathway in insects. Here we show that the Drosophila Nrf2 (NF-E2-r...

The skin, the body's largest organ, plays an important role in the biotransformation/detoxification and elimination of xenobiotics and endogenous toxic substances, but its role in oxidative stress and insulin resistance is unclear. We investigated the relationship between skin detoxification and oxidative stress/insulin resistance by examining burn-induced changes in nicotinamide degradation. R...

Giardia duodenalis is an intestinal parasite that causes 200-300 million episodes of diarrhoea annually. Metronidazole (Mtz) is a front-line anti-giardial, but treatment failure is common and clinical resistance has been demonstrated. Mtz is thought to be activated within the parasite by oxidoreductase enzymes, and to kill by causing oxidative damage. In G. duodenalis, Mtz resistance involves a...

this study was undertaken to estimate specific activities of rhodanese and 3-mercaptopyruvate sulfurtransferase (mst) in different tissues of turkey. enzyme activities were determined in tissue samples from freshly killed adult male turkeys by measurement of thiocyanate amounts produced by the action of enzymes on suitable substrates. activities of rhodanese and mst in examined tissues of turke...

The major obstacle in controlling malaria is the mosquito’s resistance to insecticides, including pyrethroids. mainly due over-expression of detoxification enzymes such as cytochromes. Insecticides tolerance can be reduced by inhibitors P450s involved insecticide detoxification. Here, design potential CYP6P3 inhibitors, a homology model enzyme was constructed using crystal structure retinoic ac...

Aim: Nuclear factor E2-related factor-2 (Nrf2) regulates many cytoprotective antioxidants, and detoxifying enzymes, has been a hopeful approach for chemoprevention of cancer. We researched the chemopreventive impact watercress on DMBA-induced oxidative damage in rat liver via Nrf2/ARE signalling pathway present study. 
 Material Method: Female Wistar albino rats have categorized into three...