BACKGROUND The aim of current study was to investigate the way dose is prescribed to lung lesions during SBRT using advanced dose calculation algorithms that take into account electron transport (type B algorithms). As type A algorithms do not take into account secondary electron transport, they overestimate the dose to lung lesions. Type B algorithms are more accurate but still no consensus is...

High computational requirements restrict the use of Monte Carlo algorithms for dose estimation in a clinical setting, despite the fact that they are considered more accurate than traditional methods. The goal of this study was to compare mean tumor absorbed dose estimates using the unit density sphere model incorporated in OLINDA with previously reported dose estimates from Monte Carlo simulati...

In this work, the accuracy of the implementation of the Macro Monte Carlo electron dose calculation algorithm into the radiation therapy treatment planning system Eclipse is evaluated. This implementation - called eMC - uses a particle source based on the Rotterdam Initial Phase-Space model. A three-dimensional comparison of eMC calculated dose to dose distributions resulting from full treatmen...

objectives: the aim of this study was to verify the treatment planning systems (tpss). the next aim was to validate imsure qa software for patient-specific qa in radiotherapy clinics.  material and methods: we used imsure qa software (standard imaging, v 3.5) for verification of 92 non-imrt plans (540 fields) in 10 radiotherapy clinics. to validate the imsure, dose measurement was performed in ...

The complexity of interactions and the nature of the approximations made in the formulation of the algorithm require that the user be familiar with the limitations of various models. As computer power keeps growing, calculation algorithms are tending more towards physically based models. The nature and quantity of the data required varies according to the model which may be either measurement b...

Radiation therapy is one of the most effective means for treating cancers. An important calculation in radiation therapy is the estimation of dose distribution in the treated patient, which is key to determining the treatment outcome and potential side effects of the therapy. Biological dose – the level of biological damage (e.g., cell killing ratio, DNA damage, etc.) inflicted by the radiation...

Conventional dose calculation algorithms, such as Pencil Beam are proven effective for tumors located in homogeneous regions with similar tissue consistency such as the brain. However, these algorithms tend to overestimate the dose distribution in extracranial regions such as in the lung and head and neck regions where large inhomogeneities exist. Due to the inconsistencies seen in current calc...