Introduction: Wedge filters are used in radiotherapy to modify photon beam and improve dose uniformity in the target volume. Determination of wedge dose distribution is important to improve treatment planning accuracy. The utilization of treatment planning software to obtain dose distribution is not always available. In this work an analytical model has been developed to calcu...

  Introduction: Using beta emitter radionuclide is a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. The aim of this research is to evaluate the tissue response to beta rays of 166Ho and determine the feasibility of beta emitting radionuclide for treatment of skin cancers. Methods: In this...

Background: Radiotherapy with large mantle field is an effective technique in increasing the risk of secondary cancers among HL (Hodgkin Lymphoma) patients; therefore, it is essential to choose an effective treatment field including the least medical conditions in radiotherapy.Objective: The present study aimed to plan separate fields for neck and mediastinum using various energies, to compare ...

Research conducted to-date, makes use of the IBA-Lynx scintillating screen and radiochromic film to analyze proton field uniformity for dose-area product (DAP) determination. In this paper, machine log file based reconstruction is proposed calculate simplify measurement. order uniformity, dose distribution reconstructed on with matRad (an open source software analytical calculation in MATLAB). ...

A sensitive, simple and reproducible protocol for nanoparticle-assisted laser desorption/ionization mass spectrometry imaging technique is described. The use of commercially available TiO2 nanoparticles abolishes heterogeneous crystallization, matrix background interferences and enhances signal detection, especially in the low mass range. Molecular image normalization was based on internal stan...

Intensity-modulated radiotherapy treatment demands stringent quality assurance and accurate dose determination for delivery of highly conformal dose to the patients. Generally 3D dose distributions obtained from a treatment planning system have to be verified by dosimetric methods. Mainly, a comparison of two-dimensional calculated and measured data in several coplanar planes is performed. In p...

AIM The aim was to provide a dosimetric comparison between IMRT and RapidArc treatment plans with RPI index with simultaneous comparison of the treatment delivery time. BACKGROUND IMRT and RapidArc provide highly conformal dose distribution with good sparing of normal tissues. However, a complex spatial dosimetry of IMRT and RapidArc plans hampers the evaluation and comparison between plans c...

This study was designed to evaluate pharmacokinetics of sulphadimidine   in cockerels fed on subclinical dose of arsenic (100 ppm) in diet and to determine the protective efficacy following simultaneous dietary medication with Piper longum (pipli)   (100 ppm) in a 12-week feeding trial. Pharmacokinetic parameters were determined after single i.v. dose (50 mg/kg) of sulphadimidine ...

Introduction In this study, we aimed to calculate dose enhancement factor (DEF) for gold (Au) and iron (Fe) nanoparticles (NPs) in brachytherapy and teletherapy, using Monte Carlo (MC) method. Materials and Methods In this study, a new algorithm was introduced to calculate dose enhancement by AuNPs and FeNPs for Iridium-192 (Ir-192) brachytherapy and Cobalt-60 (Co-60) teletherapy sources, using...

This paper presents dose calculation in proton therapy using Monte Carlo method and comparison with experimental data obtained at TOHOKU University’s cyclotron and isotope center in Japan. In this way, two Monte Carlo codes, FLUKA and MCNPX, has been employed to calculate percentage depth dose, lateral dose profiles, isodose curves and secondary particles production for proton pencil and broad ...