Pediatric patients between the ages of 12 months and 17 years with a confirmed malignancy who were scheduled to receive aprepitant as part of triple therapy antiemetic prophylaxis for a cycle of moderately- or highly emetogenic chemotherapy were eligible for enrollment. Patients were evaluated for the incidence of nausea, episodes of emesis, interference with activities of daily living (ADLs), ...

Transdermal medication delivery systems provide systemic therapy by passive diffusion through the skin. They offer an alternative route of medication administration and may be well suited for patients who are unable to take or retain oral medications. Granisetron transdermal system (Sancuso(R), ProStrakan, Inc.) is the first transdermal medication patch indicated for the prevention of nausea an...

fact that Dr. Kent Spender, of Bath, had pointed out in the March 1885 number of the Practitioner, that antimony in frequently repeated smnll doses ?th of a grain of tartar emetic, every hour or two hours, has the power of completely dissipating early local inflammations. Acting on Dr. Spender's suggestion, the treatment of surgical inflammation by antimony in small doses, frequently repeated, ...

The growth profile of Bacillus cereus in ready-to-eat (RTE) food products of animal origin was examined under different temperature and incubation conditions. In sandwiches and Kimbab, B. cereus did not grow or exhibited only minimal growth at 4 and 10oC, but it grew rapidly at ambient temperature. In sandwiches, B. cereus did not grow efficiently at 25oC, however, in ham, the main ingredient o...

Nausea and vomiting are distinct symptoms, commonly occurring together but which should be assessed separately. Both are prevalent in patients with advanced cancer. Data are taken from The Cochrane Library (2010) and Ovid MEDLINE (1966-2010). Most current guidelines advocate an aetiology-based approach to the management of nausea and vomiting. Choice of anti-emetic is based on a clinical assess...

on learning the mistake made (which had ere this been discovered by the patient), administered a mustard emetic, which, to use the manager's own words, " acted to no material extent," the patient was then sent to hospital. On arrival at the hospital, at 11-15 A.M., the man was seen by Assistant Apothecary J. R. Dolby, who observing his collapsed state, gave an ounce of brandy and applied a sina...

CONTEXT AND OBJECTIVE Nausea and vomiting are major inconveniences for patients undergoing chemotherapy. Despite standard preventive treatment, chemotherapy-induced nausea and vomiting (CINV) still occurs in approximately 50% of these patients. In an attempt to optimize this treatment, we evaluated the possible effects of carbamazepine for prevention of CINV. DESIGN AND LOCATION Prospective n...

Midodrine prevents post-space flight orthostatic intolerance when testing is conducted in a controlled laboratory setting within 2-4 hours after Space Shuttle landing. It is unknown if midodrine is as effective during re-entry and immediately following landing. METHODS: Cardiovascular responses to 10 minutes of 80° head-up tilt in five male astronauts were compared before and immediately after ...

By A. R. Hall, Assistant Surgeon, lloyal Artillery. The article on tliis subject, by Assistant, Surgeon Candy, M.D., 109th Regiment, published in the Indian Medical Gazette for July, recommends a plan of treatment, which it wns to be hoped had been given up as worse than useless by those who had had experience of this disease. Blood-lettin?, tartar-emetic, and other lowering remedies hare been ...

This paper describes a specific, sensitive, semiautomated, and quantitative Hep-2 cell culture-based 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay for Bacillus cereus emetic toxin. Of nine Bacillus, Brevibacillus, and Paenibacillus species assessed for emetic toxin production, only B. cereus was cytotoxic.