Individual susceptibility to pulmonary oxygen toxicity (PO2tox) is highly variable and currently lacks a reliable biomarker for predicting hyperoxic stress. As nitric oxide (NO) involved in many respiratory system processes functions, we aimed determine if expired (FENO) levels can provide an indication of PO2tox humans. Eight U.S. Navy-trained divers volunteered as subjects. The exposures cons...

BACKGROUND Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker of airway inflammation and nitrosative stress. Previous studies have suggested a possible role of FeNO in the management of patients with pulmonary sarcoidosis, but published data are discordant. OBJECTIVES To assess the clinical usefulness of FeNO and alveolar concentration of NO (CalvNO) in sarcoidosis. METHODS ...

BACKGROUND Mylar balloons are used to collect exhaled air for analysis of fractional nitric oxide concentration (FENO). AIM We studied the effect of storage conditions on the stability of nitric oxide (NO) in mylar balloons. METHODS Exhaled air samples and calibration gases were stored in mylar balloons at 4, 21 and 37 degrees C, with or without silica gel. NO was measured after 0, 6, 9, 24...

OBJECTIVE To investigate the possible impact of long-term occupational exposure to hydrocarbons on respiratory health. METHODS Respiratory health was assessed by questionnaires, spirometry, and exhaled nitric oxide in 250 male workers from a company handling and distributing refined petroleum products (exposed) and 250 electricians (controls). Exposure to hydrocarbons was assessed by personal...

The measurement of exhaled nitric oxide (NO) has been employed in the diagnosis of specific types of airway inflammation, guiding treatment monitoring by predicting and assessing response to anti-inflammatory therapy and monitoring for compliance and detecting relapse. Various techniques are currently used to analyze exhaled NO concentrations under a range of conditions for both health and dise...

Today, exhaled nitric oxide has been studied the most, and most researches have now focused on asthma. More than a thousand different volatile organic compounds have been observed in low concentrations in normal human breath. Alkanes and methylalkanes, the majority of breath volatile organic compounds, have been increasingly used by physicians as a novel method to diagnose many diseases without...