Holographic optical coherence imaging acquires en face images from successive depths inside scattering tissue. In a study of multicellular tumor spheroids the holographic features recorded from a fixed depth are observed to be time dependent, and they may be classified as variable or persistent. The ratio of variable to persistent features, as well as speckle correlation times, provides quantit...

ARID1A is a known suppressor of tumour formation and the Human Protein Atlas antibody HPA005456 has been demonstrated in previous literature to stain tumour tissue by immunohistochemistry (IHC) in formalin-fixed paraffin embedded human tissue and human cell lines. This article details the validation of this antibody for immunohistochemistry of formalin-fixed paraffin embedded murine tissue usin...

Pathologic diagnosis requires tissue fixation for histologic and immunohistologic analysis, and formalin is routinely used for this. The disadvantage of this fixative is its inability to preserve nucleic acids. Pathologic tumor diagnosis requires extensive molecular analyses, for which formalin fixation may be not adequate. Recently, an alcohol-based fixative (molecular fixative, MF) was descri...

The question of interest in the present study is ”given a work-piece subject to prescribed loads, how to define its initial shape such that the work-piece matches a prescribed geometry after deformation?”. This question is particularly relevant in forming processes where the tolerated mismatch between the deformed and desired geometries may be lower than a Micron. To tackle this optimal shape d...

This paper is concerned with fixed-point free S-actions (smooth or locally linear) on orientable 4-manifolds. We show that the fundamental group plays a predominant role in the equivariant classification of such 4-manifolds. In particular, it is shown that for any finitely presented group with infinite center, there are at most finitely many distinct smooth (resp. topological) 4-manifolds which...

objective: : polycystic ovary syndrome (pcos) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. in this study, the effect of pcos induction was studied using estradiol valerate. materials and methods: ad...

background the association between tumor necrosis factor-alpha (tnf-α) (-308 g/a) gene polymorphisms and level of tissue destruction and periodontal disease progression is not proved. objectives the present study investigated the stereological parameters of interdental papilla in chronic periodontitis (cp) patients with tnf-α (-308 g/a) gene polymorphisms. materials and methods sixty gingiva sa...

copper sulfate is one of the most important pollutant in aquaculture systems. the aim of the present study was of the histopathological changes of some organs of common carp. copper sulphate can be considered as a toxic agent for fish.the effect of copper sulphate at 0. 0 1 mg/l as a constant bath was studied on common carp (cyprinus carpio) weighing about 100g. at 19±1°c for one month. tissue ...