Article history: Received on: 29/03/2016 Revised on: 07/07/2016 Accepted on: 08/08/2016 Available online: 26/09/2016 Objective: To evaluate acute oral toxicity (AOT), subchronic toxicity, and mutagenic potential of glycosides based standardized fenugreek (Trigonella foenum graecum L.) seeds extract (SFSE-G). Materials and Methods: The AOT, subchronic (90-day repeated dose) toxicity and mutageni...

Fenugreek (Trigonella foenum-graecum) is a medicinal plant which is widely used for its pharmacological properties. In this study the phenolic composition of fenugreek crude seeds originating from Morocco has been investigated. Extraction was performed from defatted seeds by a hydromethanolic solution using an Accelerated Solvent Extractor. HPLC technique coupled to negative ion electrospray io...

BACKGROUND & OBJECTIVES Trigonella foenum graecum commonly known as fenugreek, has been widely cultivated in Asia, Africa and Mediterranean countries for the edible and medicinal values of its seeds. Earlier reports show that fenugreek seeds provide a mastogenic effect resulting in enhanced breast size. However, very little is known about its estrogenic effect. The present study investigated th...

BACKGROUND/OBJECTIVE The purpose of the present study was to evaluate the effect of fenugreek seed extract in combination with swimming exercise compared to glibenclamide consumption on type 2 diabetic rats. DESIGN The acute toxicity test was carried out to choose the safe doses and identify the toxicity effects of the fenugreek seed extract. To investigate the hypoglycemic effect of the extr...

Background Saponins identified from fenugreek (Trigonella foenum-graecum) seeds are reported effective on dyslipidemia. However, the definite mechanism is still not elucidated systematically. In this study, we evaluate the effects of saponin extract on cholesterol absorption, metabolism, synthesis, and reverse cholesterol transport in vivo. Methods Saponin extract was prepared according to a ...

The present study was designed to explore the combined effects of a conventional antidiabetic drug, metformin (MET) and Gymnema sylvestre (GS) or Trigonella foenum graecum (TFG) extract in alloxan (ALX, 150 mg / kg body weight, IP)-induced swiss albino mice. Other than serum glucose, changes in total serum cholesterol (TC), triglyceride (TG), urea, α-amylase and alkaline phosphatase (ALP) level...

fenugreek (trigonella foenum-graecum l.), wild or cultivated, is widely distributed throughout the world and belongs to the fabacecae family. it is an old medicinal plant and has been commonly used as a traditional food and medicine. fenugreek is known to have hypoglycemic, and hypocholesterolaemic, effects. recent research has identified fenugreek as a valuable medicinal plant with potential f...

fenugreek is an medicinal plant that use in disease some therapy. this plant use  for blood lipids and sugar decreasing in diabetic and non diabetic peoples and have antioxidant and antibacterial activity. the plant contains active constituents such as alkaloids, flavonoids, steroids, saponins etc. it is an old medicinal plant. it has been commonly used as a traditional food and medicine. fenug...