This study evaluated the association of arsenic exposure, as measured in urine, with diabetes prevalence, glycated hemoglobin, and insulin resistance in American Indian adults from Arizona, Oklahoma, and North and South Dakota (1989-1991). We studied 3,925 men and women 45-74 years of age with available urine arsenic measures. Diabetes was defined as a fasting glucose level of 126 mg/dL or high...

OBJECTIVE To examine the relationship between sustained glycemic control and health care costs among patients with diabetes with an initial hemoglobin A1c≥9%. STUDY DESIGN/METHODS We conducted a retrospective analysis of administrative data from patients with diabetes and initial poor HbA1c control enrolled in a large health plan in Hawai'i (n=1304). We used propensity scores to identify a co...

Plasma glucose plays a key role in the complications of diabetes mellitus. Hemoglobin A1c (HbA1c) and circulating concentrations of advanced glycation end products (AGEs) are central to diabetes clinical care and pathophysiology. However, there is evidence for variation between individuals in the relationship of plasma glucose to both these measures and to specific complications. The glycation ...

Introduction Posttransplantation diabetes mellitus (PTDM) is a common complication among kidney transplant recipients and is associated with a higher risk of cardiovascular events and poorer graft and patient survival. The association of pretransplantation hemoglobin A1c (HbA1c) with PTDM remains unclear. Identifying recipients at greatest risk for PTDM may help guide monitoring and treatment s...

Background Adiponectin is a novel adipocyte-specific protein, which plays an important role in decreasing insulin resistance and inflammation, hence can be considered understanding the underlying mechanisms of both diabetes periodontitis. As periodontitis mellitus share common pathways pathogenesis, this study was conducted to determine effect nonsurgical periodontal therapy on adiponect...

This study addresses the possibility of medication-freemanagement type 2 diabetesmellitus (DM). Typical glucose values, in terms hemoglobin A1C (HbA1C) test resultsof less than6.0%, could be attained by consuming low carbohydrate meals and participating physical exercises without pharmaceutical adjuncts. Four to six should consumed 12 hours, preferably during days activities between morning eve...

Objective: The mechanisms underlying worse clinical outcomes in previously unrecognized diabetic (DM) patients ST-elevation myocardial infarction (STEMI) are unclear. It was hypothesized that poor chronic glucose control might be related to greater damage.
 Material and Method: 51 newly diagnosed DM with glycated hemoglobin A1c (HbA1c) > 6.5 comprised the group, 54 sex- age-matched indi...

BACKGROUND Hemoglobin (Hb) A1c is widely used as the gold standard for blood glucose level monitoring in diabetic patients. Various methods are being used in clinical laboratories for HbA1c measurement. However, the presence of Hb variants may interfere with HbA1c measurement. METHODS The HbA1c assay was performed routinely in a 55-year old woman with type 2 diabetes and hyperlipidemia that w...

accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. to evaluate the association of oxidized low- density lipoprotein (ox-ldl) with the development of diabetic nephropathy, plasma level of ox-ldl were measured in 70 diabetic patients with macro and 63...