Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and (a) the size of the virus inoculum, (b) the blood virus titer, and (c) the degree of liver necrosis. Trauma to the liver following partial hepatectomy results in a rise in SGO-T activity ...

Objective: To see the usefulness of liver biopsy in the diagnosis and to document the spectrum of paediatric liver diseases. Methods: A retrospective, cross sectional survey at Histopathology department of Army Medical College Rawalpindi from January 2000 to December 2003. The liver biopsies were taken with Menghini needle. The fixed tissues were processed under standard conditions. Results: Du...

AIM OF THE STUDY Studying the correlation between elements of metabolic syndrome and histological changes of the liver in nonalcoholic fatty liver disease. PATIENTS AND METHODS Thirty-nine patients with nonalcoholic fatty liver disease were included in our study. Inclusion criteria were: presence of liver steatosis on ultrasound in patients with waist circumference over 94 cm in men and over ...

Endotheliitis is an important histologic feature of acute cellular rejection (ACR) in the liver allograft. This change is not specific, however, and has been suggested to be associated with various liver diseases. End-stage liver disease owing to chronic hepatitis C is the leading indication for transplantation in North America, and its recurrence in allograft recipients is common. Because the ...

BACKGROUND AND OBJECTIVES We evaluated hepatitis B virus (HBV) serological markers by novel, quantitative immunoassays in order to study their behaviours and possible role in the various phases of HBV infection. STUDY DESIGN The quantitative determination of HBsAg and anti-HBc/IgM by chemiluminescent immunoassays (Abbott Architect) and the calculation of anti-HBc avidity index have been carri...

The activities of the interferon-induced enzyme 2'-5' oligoadenylate synthetase in peripheral blood mononuclear cells were determined in patients with viral hepatitis. Increased levels of the enzyme were found in patients with acute type B hepatitis at the early phase and also in those with chronic type B hepatitis at the active stage. The levels of this enzyme activity were not significantly i...

objective: to determine the prevalence of non-alcoholic fatty liver disease (nafld) in type 2 diabetic patients and to assess its possible risk factors. materials and methods: two hundred and seventy two (186 females and 86 males) diabetic patients were studied. liver ultrasound was performed along with the measurement of such labratoary tests as alanine transaminase, aspartate transaminase, al...

Chronic hepatitis is a relatively common problem; worldwide, an estimated 350 million individuals are chronically infected with hepatitis B (HBV), 170 million are chronically infected with hepatitis C (HCV), and nonalcoholic fatty liver disease is predicted to reach epidemic proportions with the rapidly increasing prevalence of obesity and type 2 diabetes mellitus. Chronic hepatitis causes rela...