Viral hepatitis is a significant disease afflicting hundreds of millions of people. Hepatitiscausing viruses initiate significant morbidity and mortality by establishing both acute and chronic infections, and several of these viruses are specifically associated with the development of hepatocellular carcinoma (HCC). Consequently, intense research efforts are focused on increasing our understand...

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OBJECTIVE To investigate the distribution of hepatitis B virus (HBV) genotypes among patients with chronic hepatitis B in Kayseri, Turkey. METHODS The study took place in the Department of Microbiology, Erciyes University, Kayseri, and Iontek Laboratory, Istanbul, Turkey, from January 2005 to October 2007. One hundred and ten patients with chronic hepatitis B were included in this study. Hepa...

Abbreviations: CHC, chronic hepatitis C; CYP, cytochrome P450; HCV, hepatitis C virus; IL, interleukin; Peg, pegylated interferon alfa; RBV, ribavirin; SVR, sustained virologic response; VDRs, vitamin D receptors; Th, helper T cell; 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)D, 1,25-dihydroxyvitamin D Corresponding author: Tae Yeob Kim Department of Internal Medicine, Hanyang University Guri Hospita...

Hepatotropic viral infections are frequent in allograft recipients and may be caused by a number of different viruses. Of these, the most important infectious agents are hepatitis B virus (HBV) and hepatitis C virus (HCV), which can cause both acute and chronic hepatitis. In addition, Hepatitis E virus (HEV), thought previously to only cause acute hepatitis in the developing world, is emerging ...

autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. hepatitis c virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis c virus infection and some autoimmune disease has been st...

This fifty-ninth volume of IARC Monographs on the Evaluation of Carcinogenic Risks ta Humans contains monographs on three human hepatotropic viruseshepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HD~ also known as the delta agent). Until now, the subjects of IARC Monographs have been mainly single chemical compounds and, to a lesser extent, groups of chemicals, complex m...

BACKGROUND Hepatitis B infection, caused by hepatitis B Virus (HBV), is one of the major global public health problems. Hepatitis B Virus genotypes appear to show varying geographic distribution with possible pathogenic and therapeutic differences. Knowledge of HBV genotypes is very important for clinical treatment. Lamivudine is a nucleoside analogue that is clinically used to treat chronic he...

Abstract Background: Distribution of hepatitis C virus genotypes varies geographically and can be associated with clinical aspects. The virus has six major genotypes and eleven sub-genotypes. According to the recent studies, in hepatitis C patients, treatment duration and ribavirin dosage should be determined based on the type of virus genotype. Be...