a novel series of azolylalkylthio, -sulfoxy, and-sulfonyl compounds was designed, synthesized, and evaluated for antipicornaviral activity. two compounds (4i and 4 1) exhibited significant activity against various serotypes of human rhinovirus (hrv). it was found that incorporation of hydrophobic azoles such as 3-methylisoxazole or 4-methylthiazole led to increased activity. in addition, activi...
