Background: Achillea talagonica (Asteraceae) is an endemic herbaceous plant in Iran with small yellow flowers and several times pinnately divided leaves in worm shape. The plant was found to be cytotoxic in our previous studies.   Materials and Methods: A. talagonica was collected in May 2005 from Talegan in north of Iran during the full flowering stage. Dried aerial parts of the plant were r...

4-Hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one has been proposed to be a reactive metabolite of the anti-epileptic drug felbamate [Thompson et al. (1996) Chem. Res. Toxicol. 9, 1225-1229]. 4-Hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one exists in equilibrium with 3-oxo-2-phenylpropyl aminooate, which is known to eliminate to generate 2-phenylpropenal. Thus, this species is postulated to be a latent ...

Episesamin is an isomer of sesamin, resulting from the refining process of non-roasted sesame seed oil. Episesamin has two methylendioxyphenyl groups on exo and endo faces of the bicyclic skeleton. The side methylendioxyphenyl group was metabolized by cytochrome-P450. Seven metabolites of episesamin were found in rat bile after treatment with glucuronidase/arylsulfatase and were identified usin...

A new tetra-dentate unsymmetrical Schiff base, C(20)H(15)BrN(2)O(2), has been synthesized from 4-bromo-o-phenyl-enediamine and salicylaldehyde in refluxing ethanol. The dihedral angles between the two hydroxy-phenyl rings and the bromo-o-phenyl-enediiminatoin group are 68.6 (1) and 8.7 (1)°; the dihedral angle between the two hydroxy-phenyl rings is 70.3 (1)°. There are two relatively strong in...

background: achillea talagonica (asteraceae) is an endemic herbaceous plant in iran with small yellow flowers and several times pinnately divided leaves in worm shape. the plant was found to be cytotoxic in our previous studies.   materials and methods: a. talagonica was collected in may 2005 from talegan in north of iran during the full flowering stage. dried aerial parts of the plant were red...

straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furnished ...

Furan-2,5-diylbis(phenylmethanol) is a key intermediate to access sub(oxa)porphyrins. Previously, this was accessible from fossil-derived furan using highly dangerous lithium reagents. Presently, we have produced cashew apple bagasse (CAB), via the formation of 5-hydroxymethylfurfural (HMF). CAB non-food biomass containing cellulose and hemicellulose. From CAB, obtained HMF in yield 310 mg/g CA...

Porphyrins bearing bulky alkoxyphenyl substituents at two of the four meso-positions and phenyl phosphonates at the other two have been prepared and used as building blocks for layer-by-layer assembly of conductive-glass-supported thin films via zirconium phosphonate chemistry. Thin-film characterization shows that the addition of sterically demanding 2,6-di(n-hexoxy)phenyl substituents to the ...