objectives: the aim of this research was the development of 111in-labeled porphyrins as possible radiopharmaceuticals for the imaging of tumors. methods: ligands, 5, 10, 15, 20-tetrakis (3, 5-dihydroxyphenyl) porphyrin) (tdhpp), 5, 10, 15, 20-tetrakis (4-hydroxyphenyl) porphyrin (thpp) and 5, 10, 15, 20-tetrakis (3,4-dimethoxyphenyl) porphyrin) (tdmpp) were labeled with 111incl3 (produced from ...

Abstract. Biotransformations are chemical reactions carried out by microorganisms on organic substrates. can be regio-, chemo-, stereo- and enantio-selective. Bioreductions of great interest to the food pharmaceutical industries as they help reduce costs impacts environment. In this work, following biotransformations chalcones were performed: (2E)-1-(4-hydroxy-phenyl)-3-(2-methoxy-phenyl)-prop-...

Objectives: The aim of this research was the development of 111In-labeled porphyrins as possible radiopharmaceuticals for the imaging of tumors. Methods: Ligands, 5, 10, 15, 20-tetrakis (3, 5-dihydroxyphenyl) porphyrin) (TDHPP), 5, 10, 15, 20-tetrakis (4-hydroxyphenyl) porphyrin (THPP) and 5, 10, 15, 20-tetrakis (3,4-dimethoxyphenyl) porphyrin) (TDMPP) were labeled with 111InCl3 (produced from ...

The proton-ligand and metal-ligand stability constants of the complexes of Cu(II), Ni(II),Co(II) with 1-Benzothiazol2-yl-3-(2-hydroxy phenyl)-5-(4-methoxy phenyl) pyrazoline (L), 1-Benzothiazol-2-yl-3-(2-hydroxy phenyl)-5-phenyl pyrazoline (L), 1-Benzothiazol-2-yl-3-(2-hydroxy phenyl)-5-(4-chloro phenyl) pyrazoline(L), 1-Benzothiazol-2-yl3-(2-hydroxy-5-methyl phenyl)-5-(4-methoxy phenyl) pyrazo...

The title compound, C(22)H(18)N(2)O(2), was derived from 1-(2-hydroxy-phen-yl)-3-(4-methoxy-phen-yl)propane-1,3-dione. The central pyrazole ring forms dihedral angles of 16.83 (5), 48.97 (4) and 51.68 (4)°, respectively, with the methoxy-phenyl, phenyl and hydroxy-phenyl rings. The crystal packing is stabilized by O-H⋯N hydrogen bonding.

The synthesis of new trans A(2)B(2)-substituted porphyrins bearing oxygenic substituent (methoxy, acetoxy, hydroxy) at the periphery of the ring are described. All of the synthesized products were characterized by (1)H-N.M.R., (13)C-N.M.R., and H.R.M.S. Electrochemical studies revealed two one-electron oxidations and two reductions. In addition, the X-ray structure of one methoxy-derivative was...

The resinous wood of Aquilaria sinensis, known as agarwood (Chen Xiang in Chinese), is traditionally used for the treatment of abdominal pain, vomiting, circulatory disorders, and dyspnea. Four new 2-(2-phenylethyl)-4H-chromen-4-one derivatives, namely 7-methoxy-2-[2-(4'-hydroxy-phenyl)ethyl]chromone (1), 7-hydroxy-2-[2-(4'-methoxyphenyl)ethyl]chromone (2), 5,6-dihydroxy- 2-[2-(3'-hydroxy-4'-me...

Many benzo[b]furan lignans are known to be biologically active in nature. 2-(3'-Methoxy-4'-hydroxy-phenyl)-5-(3-hydroxypropyl)-7-methoxy-benzo[b]furan-3-carbaldehyde (XH-14) is found as a bioactive component isolated from the plant Salvia miltiorrhiza, commonly known as Danshen, which is a traditional Chinese medicine that is used as a cardiovascular medication. This study examined whether 3 di...

The relationship between the antibacterial activity and structure of 9-O,9'-O-demethyl (+)-virgatusin (Virg 3) was examined. The conversion of hydroxy groups on the 9 and 9' positions to amino groups increased the activity. It was found that the 3'-methoxy group was more important for higher activity than the 4'-methoxy group on the 7'-phenyl group, and that the 3,4-methylenedioxy group on the ...