background: meict is the first chlorotoxin-like peptide isolated from the iranian scorpion mesobuthus eupeus. chlorotoxin (ctx) is a neurotoxin that specially binds to (mmp-2) on ma-lignant cells and now is used in treatment of glioma. in the present study, we have used homology modeling to propose the 3d structure of meictand analyze its interaction with mmp-2 and its snp types. methods:the st...

many graph theoretical parameters have been used to describe the vulnerability of communication networks, including toughness, binding number, rate of disruption, neighbor-connectivity, integrity, mean integrity, edgeconnectivity vector, l-connectivity and tenacity. in this paper we discuss integrity and its properties in vulnerability calculation. the integrity of a graph g, i(g), is defined t...

Large surveys of star-forming regions have unveiled power-law correlations between the stellar mass and disc parameters, such as $M_{\mathrm{d}} \propto {M_{\star}}^{\lambda_{\mathrm{m}}}$ accretion rate $\dot M {M_{\star}}^{\lambda_{\mathrm{acc}}}$. The observed slopes appear to be increasing with time, but reason behind establishment these their subsequent evolution is still uncertain. We con...

a simple, clean, and environmentally benign three-component process for the synthesis of 2-amino-4hchromenes using [mim]cl, as an efficient catalyst under solvent-free conditions are described. a wide range of aromatic aldehydes easily undergoes condensations with 1-naphthol and malononitrile under solvent-free conditions to afford the desired products of good purity in excellent yields. taking...

We searched for long-duration microlensing events originating from intermediate-mass black holes (BH) in the halo of Milky Way, using archival data EROS-2 and MACHO photometric surveys towards Large Magellanic Cloud (LMC). combined these two to create a common database light curves 14.1 million objects LMC, covering total duration 10.6 years, with flux series measured four wide passbands. carri...

The submodules with the property of the title ( a submodule $N$ of an $R$-module $M$ is called strongly dense in $M$, denoted by $Nleq_{sd}M$, if for any index set $I$, $prod _{I}Nleq_{d}prod _{I}M$) are introduced and fully investigated. It is shown that for each submodule $N$ of $M$ there exists the smallest subset $D'subseteq M$ such that $N+D'$ is a strongly dense submodule of $M$ and $D'bi...