The purpose of this study was to examine the feasibility of interstitial MR lymphography using Superparamagnetic Iron Oxide (SPIO) to detect sentinel lymph nodes (SLNs) in head and neck cancer. For two patients with cT2N0 squamous cell carcinoma of the tongue, the submucosal injection of SPIO as well as sentinel lymph node navigation surgery (SLNNS) was performed before undergoing surgical trea...

Concentrations of total non-heme iron and ferritin iron were determined for whole livers and isolated Kupffer cells of rats before and after iron treatment. Rats were injected either once, with iron dextran (25 mg of iron), or multiple times, with hemoglobin (totaling 16 mg of iron) or iron dextran (totaling 140 mg of iron), 1 or 16 to 20 weeks before use. Particularly at the highest iron dosag...

objective(s) previous studies have demonstrated that the nitric oxide (no) dependent death of murine peritoneal macrophages activated in vitro with ifn-g and lps is mediated through apoptosis. in the present study, we investigated the synergistic effect of lps, ifn-g and iron on no production and apoptosis. materials and methods after determination of iron cytotoxicity, the peritoneal macrophag...

objective(s): pseudomonas aeruginosa is a nosocomial pathogen resistant to most antimicrobial treatments. furthermore, it persists in adverse environments thereby forming biofilms on various surfaces. researchers have therefore focused on antibiofilm strategies using nanoparticles due to their unique physicochemical properties. superparamagnetic iron oxide nanoparticles (sionps) have recently s...

Computational studies have attracted the attention of researchers to understand the structural behavior of the molecules. These methods grade complex systems for novel properties with new predictions in areas of physics, chemistry and biology useful for conduct of experimental studies. Nanoparticles in present day technologies have become integral part in diverse areas of science mostly with me...

Superparamagnetic iron oxide nanoparticles have been established as sensitive probes for magnetic resonance imaging (MRI). While the majority of specific nanosensors are based on sterically stabilized iron oxide particles, the focus of this review is on the use of very small iron oxide particles (VSOPs) that are electrostatically stabilized by an anionic citrate acid shell. We used VSOPs to dev...

We report the synthesis and properties of rod-shaped gold/iron oxide nanomotors that are powered by visible light in dilute hydrogen peroxide solutions. Electrochemical measurements confirmed that the light-driven nanomotors operate by a self-electrophoretic mechanism, modulated by the photovoltage and the photoconductivity of gold/iron oxide. Due to the magnetism of iron oxide, the nanomotors ...