OBJECTIVE To determine the effectiveness of increasing the dietary content of soluble fibre (psyllium) or insoluble fibre (bran) in patients with irritable bowel syndrome. DESIGN Randomised controlled trial. SETTING General practice. PARTICIPANTS 275 patients aged 18-65 years with irritable bowel syndrome. INTERVENTIONS 12 weeks of treatment with 10 g psyllium (n=85), 10 g bran (n=97), ...

Studies from the Western hemisphere have established the efficacy and safety of tegaserod in women with irritable bowel syndrome and constipation. This review summarizes the results of recent studies from around the world that confirm the efficacy and safety of tegaserod, and expand our understanding of the role of this drug in the treatment of patients with irritable bowel syndrome.

OBJECTIVES Revisions of the diagnostic criteria for irritable bowel syndrome have led to varying prevalence estimates. The Rome III criteria require a lower symptom frequency than Rome II (at least 10% of the time for Rome III, compared with at least 25% of the time for Rome II). In an epidemiological survey of a representative sample of Israeli adults using Rome II, we reported the prevalence ...

Irritable bowel syndrome is one of the most common gastrointestinal disorders in developed nations. It is characterized by abdominal pain, altered bowel habits, and bloating. Several non-pharmacological and pharmacological agents, which target the peripheral gastrointestinal system and central nervous system, are used to treat the syndrome. The individual and societal impact of investigating an...

43 INTRODUCTION Irritable bowel syndrome is a gastrointestinal disorder characterized by an alteration in bowel habit with abdominal pain in the absence of detectable structural disease (1). It is characterized by abdominal pain or discomfort in association with diarrhea, constipation, alternating diarrhea and constipation, or a mixture of these symptoms. It occurs in approximately 10%–20% of t...

Introduction: Irritable bowel syndrome is the most common, costly, and disabling dysfunction of the gastrointestinal tract. Mental disorders can be one of the main factors in the onset, continuation, or exacerbation of gastrointestinal signs and symptoms in people with this syndrome. Commitment and acceptance therapy is a mixture of four approaches of awareness, acceptance, commitment, and beha...

conclusions the results of the study were indicative of improvement and symptom relief in the majority of patients and it seems that treatment prolongation up to six months could be a key factor to achieve better clinical responses. it is recommended that further randomized clinical trials evaluate this therapeutic regimen. background the current study aimed to evaluate the efficacy of mesalazi...