Restriction endonuclease fragment length polymorphism (RFLP) is useful for the epidemiological study of herpes simplex virus type 1 (HSV-1). We report here the identification of a major BglII RFLP variant of HSV-1, designated BgKL, found in 27.0% of 636 HSV-1 clinical isolates. We have also established its geographic distribution in Japan. BgKL has an unusually large BglII K fragment. SalI clea...

We present LHIP, a system for incremental grammar development using an extended DCG formalism. The system uses a robust island-based parsing method controlled by user-deened performance thresholds. 1 LHIP Overview This paper describes LHIP (Left-Head corner Island Parser), a parser designed for broad-coverage handling of unrestricted text. The system interprets an extended DCG formalism to prod...

High elevation montane areas are called "sky islands" when they occur as a series of high mountains separated by lowland valleys. Different climatic conditions at high elevations makes sky islands a specialized type of habitat, rendering them naturally fragmented compared to more continuous habitat at lower elevations. Species in sky islands face unsuitable climate in the intervening valleys wh...

Adaptive radiation is a common mode of speciation among plants endemic to oceanic islands. This pattern is one of cladogenesis, or splitting of the founder population, into diverse lineages in divergent habitats. In contrast, endemic species have also evolved primarily by simple transformations from progenitors in source regions. This is anagenesis, whereby the founding population changes genet...

Aim The taxon cycle hypothesis describes the cyclic movement of taxa during range expansion and contraction, accompanied by an evolutionary shift from open and often coastal vegetation to closed, and often inland forest vegetation in island systems. The Hawaiian Archipelago is an ideal system to test this hypothesis given the linear fashion of island formation and a relatively well-understood g...

The urbanization effects on land surface phenology (LSP) have been investigated by many studies, but few studies focused on the temporal variations of urbanization effects on LSP. In this study, we used the MODIS EVI, MODIS LST data and China’s Land Use/Cover Datasets (CLUDs) to investigate the temporal variations of urban heat island intensity and urbanization effects on LSP in Northeast China...

A new computational method for creating all-hex meshes of thin-walled solids is presented. The proposed method creates an all-hex mesh in a three-step process. First, a tet mesh of the target geometric domain is created, and a layer of prism elements is inserted on the boundary of the mesh. Second, a sequence of novel topological transformations and smoothing operations is applied to reduce the...

Combined genetic and epigenetic analysis of sporadic colon cancer suggest that it can no longer be viewed as a single disease. There are at least three different subsets with distinct clinico-pathologic features, with important implications for preventions, screening, and therapy.

A increasing chorus of voices in the last few years has been telling us that the book is dead, and that hypertext and hypermedia will bring about fundamental changes in reading and writing. Also in prospect are radical changes in learning: the introduction of the computer will force teachers to rethink their practices, while students will be empowered to learn in new ways. Although this perspec...