Keratitis-ichthyosis-deafness (KID) syndrome is an ectodermal dysplasia caused by dominant mutations of connexin26 (Cx26). Loss of Cx26 function causes nonsyndromic sensorineural deafness, without consequence in the epidermis. Functional analyses have revealed that a majority of KID-causing mutations confer a novel expansion of hemichannel activity, mediated by connexin channels in a nonjunctio...

abstractbackground: the survival rate of preterm and low-birth-weight (lbw) infants depends on various factors such as birth weight, gestational age, and quality of care. the present study aimed at evaluating the survival rate of preterm and lbw infants, predictive factors, and the risk of mortality in three training hospitals of mashhad and tabriz cities.methods: this prospective, cohort study...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 aim : the aim of this study was to describe our results and investigate the survival of below - 18 - year - old patients undergoing lrdlt and the factors affecting this. background : living related donor liver transplantation (lrdlt) has become a good option to provide suitable grafts for children with liver diseases. using t...

Genetic correlations of selection indices and the traits considered in these indices with mature weight (MW) of Nelore females and correlated responses were estimated to determine whether current selection practices will result in an undesired correlated response in MW. Genetic trends for weaning and yearling indices and MW were also estimated. Data from 612,244 Nelore animals born between 1984...

this study was carried out to determine the effects of immunogen as a prebiotic on growth-related parameters and gut micro-flora in r. kutum fry. a basal diet was formulated using common feed ingredients supplemented with immunogen at 0, 1, 1.5, and 2 g kg-1 leading to four experimental diets.  fish were randomly distributed in 500 l fiberglass tanks (1×1×0.5 m). the experiment lasted for eight ...

SIAH proteins are the human members of an highly conserved family of E3 ubiquitin ligases. Several data suggest that SIAH proteins may have a role in tumor suppression and apoptosis. Previously, we reported that SIAH-1 induces the degradation of Kid (KIF22), a chromokinesin protein implicated in the normal progression of mitosis and meiosis, by the ubiquitin proteasome pathway. In human breast ...