Background: Royal jelly has been shown to have antioxidant and antidiabetic effects. The objective of this study was to evaluate the protective effect of RJ against kidney damage in streptozotocin induced diabetic rats. Methods: Thirty two male Wistar rats were divided randomly into four groups (n=8 per group). Normal control and diabetic control groups received 1cc/day distilled water, norm...

There is little clinical data of how hypertension may influence individuals with nephron deficiency in the context of being born with a single kidney. We recently developed a new rat model (the heterogeneous stock-derived model of unilateral renal agenesis rat) that is born with a single kidney and exhibits progressive kidney injury and decline in kidney function with age. We hypothesized that ...

In advanced chronic kidney disease, obesity may bring a survival advantage, but many transplant centres demand weight loss before wait-listing for kidney graft. The case here described regards a 71-year-old man, with obesity-related glomerulopathy; referral data were: weight 110 kg, Body Mass Index (BMI) 37 kg/m², serum creatinine (sCr) 5 mg/dL, estimated glomerular filtration rate (eGFR) 23 mL...

Cylindrospermopsin (CYN) is a toxin with world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, toxicity studies are needed to complete its toxicological profile. In this sense, vivo oral pure CYN scarce. The aim of work was perform repeated dose 28-day study rats following OECD guideline 407 provide information on health hazard likely arise from kind ...

Introduction: Renal ischemia reperfusion (I/R) caused kidney injury gender dependently. High fat diet (HFD) contributes the development of renal dysfunction. L-arginine (L-arg) and regular exercise are recognized to be protective in I/R and lipotoxicity. We compared the role of aerobic exercise and L-arg supplementation against renal I/R in male and female rats fed with HFD. Methods: 54 adult ...

The objective of the present study was to investigate the effect of raw and differently processed [aqueous heating, dehulled, and dry heating (toasted)] kidney bean meals on the performance, weights, and histology of internal organs of broiler chicken. The feeding trial lasted for 56 d. Two hundred twenty-five 1-d-old broiler chicks (Anak strain) were used for the study. There were 5 treatment ...