Accurate chromosome segregation depends on proper kinetochore-microtubule attachment. Upon microtubule interaction, kinetochores are subjected to forces generated by the microtubules. In this work, we used laser ablation to sever microtubules attached to a merotelic kinetochore, which is laterally stretched by opposing pulling forces exerted by microtubules, and inferred the mechanical response...

Cryptococcus is a pathogenic fungus that can cause various infections mainly in an immunocompromised host. Cryptococcal yeasts are easily inhaled, so pulmonary infection the most commonly encountered, but immunocompetent status, primary cryptococcosis occurs rarely pharyngo-epiglottic fold. A 75-year-old male came to our clinic with complaint of foreign body sensation throat lasted for three mo...

background: musculoskeletal symptoms are the main cause of loss of working time, and increase in labor costs. poor posture is the most important risk factor for work-related musculoskeletal symptoms. this study aimed at evaluating the role of ergonomic risk factors in different surgical (open surgery, laparoscopy, and microsurgery) in the frequency or resonance frequency of musculoskeletal symp...

1 Department of Plastic Surgery and Reconstructive Microsurgery, County Emergency Hospital, Ploiesti, Romania 2 „Carol Davila” Universiy of Medicine and Pharmacy, Bucharest, Romania 3 Department of Dermatovenerology, Elias Emergency Clinical Hospital, Bucharest, Romania 4 Department of Plastic Surgery and Reconstructive Microsurgery, Emergency County Hospital Constanta, Romania 5 Department of ...

We produce minimally disruptive breakdown in water by using tightly focused 100-fs laser pulses and demonstrate the potential use of this technique in microsurgery of the eye. Using time-resolved imaging and piezoelectric pressure detection, we measure the magnitude and speed of propagation of the pressure wave produced in the breakdown. Compared with breakdown with longer pulses, here there is...

A patient was encountered with verrucous carcinoma of the larynx that presented as a hairy whitish tumor. There was a recurrence because simple excision with forceps by endolaryngeal microsurgery was performed in the first operation. However, in the second operation endolaryngeal microscopic laser surgery using a direct laryngoscope was performed and followed by adjuvant chemotherapy with oral ...

It has been reported that nontransformed mammalian cells become arrested during G1 in the absence of centrioles (Hinchcliffe, E., F. Miller, M. Cham, A. Khodjakov, and G. Sluder. 2001. Science. 291:1547-1550). Here, we show that removal of resident centrioles (by laser ablation or needle microsurgery) does not impede cell cycle progression in HeLa cells. HeLa cells born without centrosomes, lat...

OBJECTIVES/HYPOTHESIS To evaluate the outcomes of transoral laser microsurgery (TLM) for T1 glottic carcinoma using longitudinal voice analysis. STUDY DESIGN Retrospective analysis of medical records. METHODS We conducted a retrospective review of 57 patients (50 T1a, seven T1b) who underwent TLM for T1 glottic carcinoma, and longitudinal voice analysis was performed before surgery, during ...