Age-related macular degeneration (AMD) is the primary cause of irreversible photoreceptors loss in adult patients and current therapies are limited. Increased levels of matrix metalloproteinases (MMPs) have been documented in neovascularization of severe ocular pathologies such as AMD and proliferative diabetic retinopathy. We report here that MMP-9 (gelatinase B) expression is induced and temp...

Minimally invasive therapies are gaining increasing attention as an alternative to standard surgical therapies in the treatment of primary hepatocellular carcinoma. These include therapies administered transcatheterally (arterial embolization, intraarterial chemoinfusion, and combination chemoembolization) and percutaneously (chemical ablation with ethanol or acetic acid, and thermal ablation w...

introduction: the aim of this study is to evaluate the effects of low-level neodymium-doped yttrium aluminium garnet (nd:yag) laser irradiation on orthodontic tooth movement and histological examination. methods: eleven male wistar rats (aged 10 weeks) were included. to produce experimental tooth movement in rats, 10 g force was applied to maxillary first molars with nickel titanium closed coil...

This work studied the effect of additions of carbon dioxide to argon shielding gas on the weld shape and microstructure of ST14 steel in pulsed Nd: YAG laser welding. By additions of carbon dioxide up to 15%,the weld area and depth/width ratio decreases while rising of carbon dioxide up to 25% causes increasing of weld area and depth/width ratio. It is observed that the weld metal microstructur...

Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus that can cause permanent scarring. Treatment of DLE includes protection from sunlight and artificial sources of ultraviolet light, as well as systemic and topical medications. The first-line standard therapies are antimalarials and topical steroids. Other systemic therapies include systemic steroid, azathioprine, dapsone, an...

Introduction Melasma and postinflammatory hyperpigmentation (PIH) are conditions commonly encountered by dermatologists, they often distressing to patients. While PIH can improve with time once the inflammatory process is controlled, melasma a condition that requires prolonged treatment maintenance. There numerous options, ranging from UV protection topical therapies (such as hydroquinone), mor...

IMPORTANCE Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE To review the use and efficacy of lasers for treating nongenital cutaneous warts. ...

Objective: The aim of this study was to compare switched on and switched off (sham) low-level laser therapy (LLLT) in the treatment of drug-induced hyposalivation. Background Data: Hyposalivation is decreased salivary flow rate most frequently present in patients who take a lot of medication, suffer from Sjögren’s syndrome, or were irradiated. Available therapies provide only short-term relief....

In fifty years, laser technology has made great progress, and its many applications make it essential in everyday life. However, this technology is still open to numerous developments. Across multiple applications, there is particular focus in the field of medicine, for diagnosis for tailored therapies, and as a research tool in biology. Whereas its use is now well-demonstrated in ophthalmologi...