T ERMATOSES of diverse etiology have been -I-~ reported to give rise to skin and mucous membrane lesions whose morphology, symptomatology, course, and microscopic picture cannot be distinguished from lichen planus. Drugs,1-6 vaccines,7 contact with chemicals,8-'3 and exposure to ultraviolet light and Grenz rays14 are prominent among the causative agents which have been observed to produce liche...

INTRODUCTION Lichen planus has been reported in association with liver diseases. Clinical signs such as jaundice may not be reliable indicator of ongoing inflammation or the presence of an ongoing liver disease. Liver function test in spite of its variability may serve as a more reliable indicator of liver disease. The objective of this study is to assess the discriminant power of liver enzymes...

Oral lichen planus is a chronic inflammatory immune-mediated disease. ICAM-1 and VCAM-1 are vascular adhesion molecules that their receptors are located on endothelial cells and leukocytes. The aim of this study is the immunohistochemical evaluation of VCAM1 and ICAM1 in oral lichen planus and to compare these two markers with normal mucosa for evaluation of angiogenesis. This descriptive-analy...

INTRODUCTION There are few reports concerning association between primary biliary cirrhosis (PBC) and lichen planus. In addition, there is only one report about lichen planus after liver transplantation. CASE PRESENTATION We describe a case of oral lichen planus (OLP) accompanied with PBC that resolved following liver transplantation 14 years later. This patient received immunosuppressive dru...

Dental Update – November 2002 Abstract: Lichen planus is a relatively common, often clinically distinctive, mucocutaneous condition with an uncertain aetiology. One variant of lichen planus is the so-called ‘lichenoid drug eruption’. In contrast to idiopathic lichen planus, lichenoid drug eruptions, where practicable, may be managed by substitution of the offending drug. The dental clinician is...

Lichen planus is a mucocutaneous disease that predominantly affects older patients and occurs much less frequently in the pediatric population. Furthermore, oral lichen planus is extremely rare in childhood with very few cases cited in the literature. The intention of this paper is to contribute two clinically and histologically documented cases of juvenile oral lichen planus cases to the liter...

The distribution of IgM and IgG in 20 cases of lichen planus and five cases of non-specific inflammation were studied by the unlabelled antibody-enzyme (PAP) technique. Routine paraffin sections were used. In lichen planus deposits of immunoglobulins were seen in and around epithelial cells, in colloid bodies, at epidermo-dermal junctions, and in some inflammatory cells. All cases examined for ...

Lichen planus is a rare inflammatory disease that affects the skin, mucous membranes, nails, and hair. It is characterized by shiny, polygonal, itching papules which vary in size and location. In the Anglo-American literature, the clinical characteristics of lichen planus are known by the four p's – purple, polygonal, pruritic, papules.The etiology and pathogenesis of disease are not well under...

BACKGROUND Oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. The role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. We aimed to evaluate the serum level of VEGF in patients with oral lichen planus compared with normal ind...

BACKGROUND AND AIMS The purpose of this study was to determine efficacy of 19% Elaeagnus angustifolia (EA) topical gel in the treatment of symptomatic oral lichen planus. MATERIALS AND METHODS Patients with symptomatic oral lichen planus referring to the Department of Oral Medicine, Fac-ulty of Dentistry at Shahid Beheshti University of Medical Sciences were asked to participate in the study....