This study was undertaken to assess the frequency of decreased bone mineral density and its risk factors as well as its impact on the quality of life during childhood among hemophiliac patients. Materials and Methods: Thirty seven children with severe hemophilia A and B, referred to Mofid Children’s Hospital during 2010, were selected. For all patients the joint score, body mass indexes, bone...

Leukemia is the most common childhood cancer and accounts for 30-40% of all malignancies. A retrospective review  was performed of the hospital records of 9 children, 6 boys and 3 girls, aged  from 2.5 to 15 years with ALL initially referred to Nemazee hospital Nuclear medicine center for whole body bone scanning between 2000 and 2002. Bone marrow pathology established ALL (L1) in two and ALL (...

background and aims. autogenous bone graft is commonly used for reconstruction of bone defects in routine surgical procedures. the complexity of producing bone grafts and their application has lead to the use of human bone matrix gelatin (hbmg). the present study was conducted to compare the efficacy of hbmg and autograft on the reconstruction of bone defects in rats. materials and methods. in ...

objective(s):to study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. materials and methods:forty new zealand rabbits were randomly divided into five groups with eight rabbits in each group. for each group, bone defects were generated in the left humerus of four rabbits, and in the right humerus of the other four rabbits. to t...

Avascular necrosis of the femoral head (ANFH) is a pathologic process that results from interruption of blood supply to the femur bone resulting in the death of bone cells and collapse of the femoral head. Nontraumatic ANFH continuesto be a significant challenge to orthopedic surgeons. While the exact mechanisms remain elusive, many new insights have emerged from research in the last decade tha...

Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99mTc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bo...

Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...