Mohsen KhoshNiyat Nikoo

Associate professor of Endocrinology, Endocrinology and Metabolism Research Center, Tehran University of Medical sciences, Tehran, Iran

[ 1 ] - Evaluation of the effect of using Symptom Focused Management Model (SFMM) on the amount of HbA1c, knowledge, and self care behavior of type 2 diabetes patients

Background: Diabetes control needs more effective educational programs. Self-care education is an important factor in diabetes control. It seems that the symptoms can be the proper stimulus for the direction toward self-care. Aim: To evaluate the effects of the using SFMM on HbA1c, knowledge, self care practices, and symptoms of type2 diabetic patients. Methods: Seventy type 2 diabetic patients...

[ 2 ] - Recommended guideline for designing and interpreting of Ramadan fasting studies in medical research

Ramadan fasting is specific intermittent fasting comprising significant changes in routine lifestyle pattern and may affect body homeostasis and metabolism. In spite of several studies conducted on the effects of Ramadan fasting on various aspects of health and disease, because of heterogeneity in methodology and procedures (sometimes inevitable), a comprehensive concluding for reliable results...

[ 3 ] - Misconceptions and negative attitudes towards the metabolic effects of Ramadan fasting, resulting in fasting avoidance

The aim of this study was to assess public knowledge about the effects of Ramadan fasting on various aspects of health and its association with fasting decision-making. This cross-sectional study was conducted on 600 subjects. The association between fasting and participants’ knowledge and attitudes toward Ramadan fasting, anthropometric measurements, physical activity, depression, anxiety, str...

[ 4 ] - وضعیت روی و ارتباط آن با تراکم استخوانی در بیماران 20-10 ساله تالاسمی ماژور

زمینه و هدف: مطالعات اخیر نشاندهنده نقش عناصر کمیاب در متابولیسم استخوان می‌باشد. این مطالعه وضعیت روی سرم و ارتباط آن را با اختلالات تراکم استخوان (BMD) در بیماران تالاسمی بررسی می‌نماید. روش بررسی: در 131 بیمار مبتلا به β تالاسمی که وابسته به تزریق خون بودند و تمام این بیماران در محدوده سنی 20-10 سال قرار داشتند، سطح سرمی روی با روش (F-AAS) Flame -Atomic Absorption SPectrophotometry ان...

[ 5 ] - مقادیر نرمال توده استخوانی در نوجوانان ایرانی 20-10 ساله

  چکیده   زمینه و هدف : هر چند که پوکی استخوان در اطفال و نوجوانان شایع نیست اما از آنجا که به نظر می‌آید میزان تراکم مواد معدنی استخوان در این گروه سنی می‌تواند پیشگویی‌کننده وضعیت آن در سالهای آینده زندگی باشد، در حال حاضر مطالعات متعددی جهت تعیین میزان تراکم استخوان در این گروه سنی انجام می‌گردد. هدف این مطالعه تعیین میزان مرجع تراکم استخوان به روش DXA [1] در جمعیت 20-10 ساله تهران بود.   رو...

[ 6 ] - تبیین سیاست‌های اولویت‌دار جمهوری اسلامی ایران در پیشگیری از چاقی کودکان

مقدمه: چاقی کودکان پیش زمینه‌ی مهمی برای ابتلا به چاقی در بزرگسالی و عواقب آن است بنابراین پیشگیری و کنترل چاقی در کودکان امری ضروری و لازم است. با توجه به محدودیت در منابع، لازم است مناسب‌ترین و مقرون به صرفه‌ترین برنامه‌ها و سیاست‌های پیشگیرانه تدوین و به کار گرفته شوند. مواد و روش‌ها: پس از مرور مطالعات مرتبط، برنامه‌ها و سیاست‌های کشورهای دیگر، توصیه‌های سازمان‌های بین‌المللی و با در نظر گر...

[ 7 ] - بررسی پروفایل اسیدهای آمینه‌ی سرم در نفروپاتی دیابتی

Background: Diabetic nephropathy is a chronic kidney disease and of more common complications of type 2 diabetes mellitus. The current diagnostic markers of diabetic nephropathy, albumin and creatinine, are only able to catch the disease in the stage of renal damage. The aim of this study is evaluation of targeted metabolomics of serum amino acids to identify the association of the changes of s...

[ 8 ] - فراوانی دیسکوردنس تراکم استخوانی ستون فقرات با گردن فمور و ارزیابی برخی عوامل موثر بر آن در زنان یائسه: نتایج مطالعه 11 ساله IROSTEOPs

Background: Discordance (the presence of different categories of T scores in two skeletal sites of a single patient) can affect the physician’s decision to start medication or not. The present study was therefore conducted to assess the prevalence of T-score discordance between spine and femoral neck as well as its risk factors in a group of postmenopausal Iranian women. Methods: The p...

[ 12 ] - چاپ‌زیستی اعضای بدن: از رؤیای علمی تا فناوری رو به رشد

The behavior of tissue fragments in permissive jells is like liquid drops. Under appropriate conditions this phenomenon could be used to print tissues of prescribed shape. Application of the principles of rapid prototyping to tissue engineering or robotic biofabrication is a novel technology that holds promising future in producing suitable human organs in large scale. An introductory discussio...

[ 13 ] - مقایسه وضعیت شناختی سالمندان مبتلا به دیابت نوع 2 با افراد غیر مبتلا

Background: Increasing number of people with diabetes make it the greatest world-wide epidemy which indicates importance of education in physical and mental health of the patients. Since researches report different results about cognition status of diabetic patients, this study was conducted to determine and compare cognitive status in older people with and without type 2 diabetes.Methods: In t...

[ 14 ] - راهنمای عملی دیابت ایران؛ روش‌ها و اهداف

Diabetes accounts as one of the most prevalent diseases worldwide that affects roughly 2 million people with a prevalence of 4.67% in Iran. Despite clinical knowledge of the benefits of optimal glycemic control and preventive care, current studies show that many people with diabetes don't receive such care. Changing physician behavior is a crucial step in implant of scientific evidence into imp...

[ 15 ] - نگرش بیماران در مورد حریم خصوصی و رازداری در بیمارستاهای منتخب تهران

Privacy and confidentiality are the inalienable rights of every human being to preserve his dignity. This issue should be considered in all levels of medical interventions. In the healthcare system, based on respect for privacy and confidentiality, patients decides what information to provide to their physicians. However, if a patient does not provide necessary information to his physician this...

[ 16 ] - پرداخت‌های غیررسمی در ایران: نتایج مطالعه‌ای مقطعی قبل از اجرای طرح تحول نظام سلامت

Informal payments in clinics raise ethical concerns in healthcare delivery. This cross-sectional questioner survey aims to evaluate the prevalence and related factors of informal payment in healthcare system in Iran. The study was carried out in 2013, prior to the implementation of the government' Health System Reform among physicians with different specialties. The questionnaire were distribu...

[ 23 ] - DNA Biosensor for Determination of 5-Fluorouracil based on Gold Electrode Modified with Au and Polyaniline Nanoparticles and FFT Square Wave Voltammetry

In the present study, a new biosensor for 5-Fluorouracil was described using modified goldelectrode and Fast Fourier transform square wave voltammetry (FFT SWV). Calf thymus DNAimmobilization was on a gold electrode decorated with polyaniline and gold nanoparticles. Theelectrochemical characteristics of the electrodes were investigated by cyclic voltammetry, andelectroch...

[ 24 ] - Improve Invisible Ink Production by the Europium Complexes

The invisible inks have many applications, including the use of banknote printing, code load, securitydocuments and much of its application in the exchange of security information. Photoluminescenceproperties of lanthanide compounds that attracted the attention of many scholars in recent decades are one ofthe important factors in drying and fluidity of the ink. The solvent eva...

[ 25 ] - پاراتورمون نوترکیب و پوکی استخوان:  مقاله مروری

Osteoporosis is a condition characterized with reduced bone density and destruction of the bone structure. The ideal treatment aims to reduce the risk of fracture while improving the density and structure of the bone. Parathormone (PTH) and its main analogue triparatide (rhPTH [1-34]) is a new class of anabolic medications which accelerates the healing process in the fractured bone through impr...

[ 26 ] - Diabetic Foot Care and Management Approaches during the Global COVID-19 Pandemic According to the International Working Group on the Diabetic Foot (IWGDF) Guidelines

Abstract: Introduction: Due to the current unpredictable changes following the global coronavirus disease (COVID-19) pandemic, significant changes have taken place in the healthcare systems. Most of the clinical and evidence-based care services for patients with diabetic foot has been disrupted. Therefore, many patients with diabetic foot ulcers cannot receive the necessary care, despite its gr...

[ 27 ] - Analysis of Scientific Products about Microbiota and Covid-19: A Scientometric Study

  Background and purpose: Gastrointestinal symptoms along with respiratory symptoms recorded in patients with Covid-19 indicate the role of microbiota in this disease. The purpose of this scientometric study was to assess the articles published on the relationship between microbiota and Covid-19 in order to control the pandemic by reaching new strategies. Materials and methods: Relevant articl...

[ 28 ] - Pharmacogenomics of glibenclamide in patients with type 2 diabetes mellitus: A systematic review

Introduction: One of the most widely used anti-diabetic drugs is sulfonylureas, which is often used as one of the first-line drugs in the treatment of type 2 diabetes. Due to the effect of the patient's genetic structure on the drug response (personalized medicine), the identification of genetic variations not only reduces the rate of adverse drug reactions but can also predict the effectivenes...

[ 29 ] - ENDOCRINOLOGY AND METABOLISM INSTITUTE OVER TIME: A QUARTER OF A CENTURY OF EXPERIENCE

Endocrinology and Metabolism Research Institute (EMRI) was established in 1993. EMRI has progressed step by step from the beginning and has reached maturity in the last 25 years. EMRI has expanded, advanced in human resources and infrastructures (laboratories and new technologies) and gained first rank in endocrine research in various fields. It has also worked with regional and international o...

[ 30 ] - ACHIEVEMENTS AND ADVANCES IN DIABETES RESEARCH OVER A QUARTER OF A CENTURY: A REVIEW OF THE AVAILABLE EVIDENCE

Background: Endocrinology and Metabolism Research Institute (EMRI) is one of the largest research institutes in Iran, which has been established to develop research strategies and manage endocrine and metabolic diseases such as diabetes. The purpose of this report is to review and summarize research activities related to diabetes over a quarter of a century at EMRI. Methods: A comprehensive se...

[ 31 ] - IMPORTANCE OF POPULATION-WIDE STUDIES IN CONTROLLING NON-COMMUNICABLE DISEASES: ACHIEVEMENTS OF NON-COMMUNICABLE DISEASES RESEARCH CENTER, ENDOCRINOLOGY AND METABOLISM RESEARCH INSTITUTE

Non-Communicable Diseases (NCDs) are the major cause of premature death and disability due to diseased globally, imposing a heavy burden on the health systems. Four main categories of NCDs are cardiovascular diseases, neoplasms, diabetes, and chronic respiratory diseases. Iran, the second greatest country in the Middle East Region, has been through an important transition period of communicable...

[ 32 ] - AN OVERVIEW OF STEM CELL AND REGENERATIVE MEDICINE RESEARCHES IN IRAN

Background: In many years, finding modern and appropriate treatments for diseases, especially chronic diseases (such as chronic metabolic diseases) have been one of the most important issues. On the other hand, limitations related to organ transplantation have made a serious need for advanced therapeutic strategies. In this respect, researchers have recognized the benefits of stem cells as a su...

[ 33 ] - CROSSING THE WAY OF PRECISION MEDICINE APPROACH IN PERSONALIZED MEDICINE RESEARCH CENTER: A SYSTEMATIC REVIEW

Background: Precision medicine is a new approach in the field of medical sciences that utilizes the genetic characteristics of each patient along with clinical information to guide decisions related to diagnosis and early treatment of diseases. The Personalized Medicine Research Center, as the only center approved by the Ministry of Health, is working on precision medicine context and producing...

[ 34 ] - SCIENTIFIC MAP OF EVIDENCE-BASED MEDICINE PRODUCTION IN TEHRAN UNIVERSITY OF MEDICAL SCIENCES IN SCOPUS DATABASE

Background: The purpose of this study is to identify patterns of information sharing in the field of evidence-based medicine to determine the main areas of evidence dissemination, including co-authorship patterns and citation networks, and to provide a scientific horizon for improving evidence-based medical research in Iran. Accordingly, evidence-based medicine related research at the Endocrino...

[ 35 ] - EVALUATION OF METABOLIC PROFILE OF PLASMA AMINO ACIDS IN DIABETIC PATIENTS WITH CARDIOVASCULAR DISEASES

Background: Diabetes mellitus is one of the most common endocrine diseases. Cardiovascular disease (CVD) is one of the leading causes of death in patients with type 2 diabetes. The aim of this study was to investigate the metabolic profile of plasma amino acids in diabetic patients with cardiovascular disease. Methods: The present study is a descriptive-analytical cross-sectional study on 140 ...

[ 36 ] - AN ESTIMATION OF CLINICAL HYPERTHYROIDISM PREVALENCE IN THE NATIONAL AND SUB-NATIONAL LEVELS IN IRAN USING CLAIMS DATA

Background: The aim of this study was to estimate the prevalence of clinical hyperthyroidism at the national and sub-national levels using the claims data. Methods: National anti-thyroid medications (methimazole and propylthiouracil) sales data in 2014 were extracted from pharmaceutical sales data that were reported by Iran's Food and Drug Administration (FDA). By using prescriptions data of S...